Asian People/genetics Genetic Predisposition to Disease Humans *Methylenetetrahydrofolate Reductase (NADPH2)/genetics Polymorphism Single Nucleotide *Urinary Bladder Neoplasms/genetics Folate Mthfr Polymorphism Urinary Neoplasms bladder cancer

Arylamine N-Acetyltransferase/*genetics Asian People/genetics Humans *Polymorphism Single Nucleotide Smoking/epidemiology Urinary Bladder Neoplasms/epidemiology/ethnology/*genetics White People/genetics Bladder cancer Meta-analysis N-acetyltransferase 2 Polymorphism competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Asian People/genetics Carcinoma Renal Cell/genetics Female Genetic Association Studies/*methods Genetic Predisposition to Disease Humans Kidney Neoplasms/genetics Male *Polymorphism Single Nucleotide Prostatic Neoplasms/genetics Urinary Bladder Neoplasms/genetics Urogenital Neoplasms/*genetics Vascular Endothelial Growth Factor A/*genetics Meta-analysis Polymorphism Urologic neoplasms Vascular endothelial growth factors

Asian People/genetics Biomarkers Tumor/*blood/urine Cystoscopy/adverse effects Humans MicroRNAs/*blood Neoplasm Staging Nuclear Proteins/urine Odds Ratio ROC Curve Regression Analysis Sensitivity and Specificity Urinalysis/methods Urinary Bladder Neoplasms/*blood/diagnosis/*genetics/urine Bladder cancer Diagnosis Meta-analysis miRNA authors declare that they have no competing interests. PUBLISHER’S NOTE: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Acetylation Arylamine N-Acetyltransferase/*genetics/metabolism Asian People/genetics Case-Control Studies China/epidemiology Genetic Association Studies Genetic Predisposition to Disease Humans Odds Ratio Phenotype *Polymorphism Single Nucleotide Risk Assessment Risk Factors Urinary Bladder Neoplasms/enzymology/ethnology/*genetics

Asian People/genetics Female Humans Male Microtubule-Associated Proteins/*genetics *Polymorphism Single Nucleotide Urinary Bladder Neoplasms/ethnology/*genetics/pathology White People/genetics