*Cystectomy/adverse effects/methods Humans Neoplasm Staging Neoplasm Residual/pathology/surgery *Reoperation/methods/statistics & numerical data *Urinary Bladder Neoplasms/pathology/surgery Cystoscopy Meta-analysis Neoplasm recurrence Urinary bladder neoplasms

Aminolevulinic Acid/*chemistry Cystoscopy/methods Humans Image Interpretation Computer-Assisted/*methods Narrow Band Imaging/methods Photosensitizing Agents/*chemistry Urinary Bladder Neoplasms/metabolism/pathology/*surgery Narrow band imaging bladder cancer diagnostic performance photodynamic diagnosis white light-guided cystoscopy

Adjuvants Immunologic/*therapeutic use Administration Intravesical BCG Vaccine/*therapeutic use Carcinoma Transitional Cell/pathology/*therapy Cystoscopy Female Humans Male Multivariate Analysis Muscle Smooth/*pathology Neoplasm Invasiveness Neoplasm Recurrence Local/*epidemiology Proportional Hazards Models Sex Factors Survival Rate Urinary Bladder Neoplasms/pathology/*therapy *Urologic Surgical Procedures Bladder cancer Gender differences Local recurrence Meta-analysis Transurethral resection of bladder tumor

Biomarkers Tumor/*urine Cystoscopy/methods *DNA Methylation Humans Urinary Bladder Neoplasms/*diagnosis/urine biomarkers methylation molecular diagnostics neoplasms urinary bladder urine analysis

Biomarkers Tumor *Cystoscopy *Cytodiagnosis Early Detection of Cancer Humans Prospective Studies Reproducibility of Results Retrospective Studies Sensitivity and Specificity Urinary Bladder Neoplasms/complications/*diagnosis/pathology Urinary Bladder Neurogenic/*complications (MeSH): neurogenic bladder bladder cancer cystoscopy screening urinary cytology

Antineoplastic Agents/*therapeutic use Carcinoma Transitional Cell/pathology/*therapy Chemotherapy Adjuvant Cystectomy Cystoscopy Humans Lymph Node Excision Muscle Smooth/*pathology *Neoadjuvant Therapy Neoplasm Invasiveness *Organ Sparing Treatments Progression-Free Survival Proportional Hazards Models *Radiotherapy Adjuvant Survival Rate Urinary Bladder Neoplasms/pathology/*therapy Bladder preserving Cancer Muscle invasive Radical cystectomy Trimodal

Asian People/genetics Biomarkers Tumor/*blood/urine Cystoscopy/adverse effects Humans MicroRNAs/*blood Neoplasm Staging Nuclear Proteins/urine Odds Ratio ROC Curve Regression Analysis Sensitivity and Specificity Urinalysis/methods Urinary Bladder Neoplasms/*blood/diagnosis/*genetics/urine Bladder cancer Diagnosis Meta-analysis miRNA authors declare that they have no competing interests. PUBLISHER’S NOTE: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Age Factors Cystoscopy/*methods Cytodiagnosis Hematuria/*complications/*diagnosis Humans Predictive Value of Tests Sex Factors Smoking Time Factors Urinary Bladder Neoplasms/*complications/diagnosis/urine bladder cancer diagnosis haematuria timeliness urinary bladder neoplasm