Muscle-invasive Bladder Cancer Radiation Therapy Guideline

NMIBC chemotherapy intravesical

NMIBC chemotherapy hyperthermia

Adult Embolization Therapeutic/*adverse effects/methods Humans Lower Urinary Tract Symptoms/*etiology Male Middle Aged Patient Reported Outcome Measures Penile Erection/physiology Prostate/blood supply Prostatic Hyperplasia/*therapy Randomized Controlled Trials as Topic Safety Treatment Outcome Benign prostatic hyperplasia Lower urinary tract symptoms Prostatic artery embolization Systematic review

Aged Drug Therapy Combination Erectile Dysfunction/*drug therapy Humans Male Middle Aged Phosphodiesterase Inhibitors Prostatic Hyperplasia/*drug therapy Tadalafil Tamsulosin Treatment Outcome Vasodilator Agents *benign prostatic hyperplasia *erectile dysfunction *meta-analysis *tadalafil *tamsulosin conflicts of interest with respect to the research authorship and/or publication of this article.

5-alpha Reductase Inhibitors/*administration & dosage Adrenergic alpha-1 Receptor Antagonists/*administration & dosage Drug Therapy Combination Dutasteride/*administration & dosage Erectile Dysfunction/chemically induced/diagnosis Humans Male Prostatic Hyperplasia/diagnosis/*drug therapy/epidemiology Randomized Controlled Trials as Topic/methods Tamsulosin/*administration & dosage Treatment Outcome Benign prostatic hyperplasia Dutasteride Meta-analysis Randomized controlled trials Tamsulosin published studies thus no ethical approval and patient consent are required. CONSENT FOR PUBLICATION: Not applicable. COMPETING INTERESTS: The authors declare that they have no competing interests. PUBLISHER’S NOTE: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Bladder Cancer Checkpoint Inhibitors Chemotherapy Immunotherapy Urothelial Cancer

Adjuvant Chemotherapy Bladder-sparing Chemoradiation Enhanced Recovery after Surgery Muscle-invasive Bladder Cancer Neoadjuvant Chemotherapy Radical Cystectomy Transurethral Resection of Bladder Tumor Trimodal Urothelial Carcinoma of Bladder Variant Histology

Anticoagulants Blood Transfusion *Deprescriptions Dysuria/epidemiology Humans Laser Therapy Male Operative Time Postoperative Complications/epidemiology Prostatic Hyperplasia Reoperation Transurethral Resection of Prostate Urethral Stricture/epidemiology Urinary Tract Infections/epidemiology Anticoagulant Benign prostate hyperplasia (BPH) Lower urinary tract symptom (LUTS) Photoselective vaporization (PVP)

Aged Catheterization Humans *Laser Therapy Lower Urinary Tract Symptoms/physiopathology Male Prostate/physiopathology Prostatic Hyperplasia/physiopathology Randomized Controlled Trials as Topic *Transurethral Resection of Prostate Treatment Outcome benign prostatic hyperplasia (BPH) button-type bipolar plasma vaporization (BTPV) lower urinary tract symptoms (LUTS) transurethral resection (TURP)

Bladder Cancer Chemotherapy Cystectomy Immune Checkpoint Inhibitors

Aged Holmium Humans *Laser Therapy Lasers Solid-State Male Postoperative Complications/etiology Prostate/*radiation effects Prostatic Hyperplasia Publication Bias Randomized Controlled Trials as Topic Thulium Treatment Outcome Efficacy Enucleation Holmium laser Meta-analysis Safety Thulium laser

Female Humans Lower Urinary Tract Symptoms/*drug therapy Male Prostatic Hyperplasia/complications/*drug therapy Randomized Controlled Trials as Topic Sexual Dysfunction Physiological Treatment Outcome

Adrenergic alpha-1 Receptor Antagonists/*administration & dosage Adrenergic beta-3 Receptor Agonists/administration & dosage Cholinergic Antagonists/administration & dosage Drug Therapy Combination Humans Lower Urinary Tract Symptoms/*drug therapy Male Phosphodiesterase 5 Inhibitors/*administration & dosage Prostatic Hyperplasia/complications Quality of Life Randomized Controlled Trials as Topic 5-alpha reductase inhibitor Lower urinary tract symptoms alpha blockers anticholinergic: systematic review benign prostatic hyperplasia randomized trials

Capsules Drugs Chinese Herbal Humans Male Prostatic Hyperplasia/*drug therapy Randomized Controlled Trials as Topic Treatment Outcome Urinary Retention benign prostatic hyperplasia meta-analysis randomized controlled trial systematic review Qianlieshutong Capsules

Embolization Therapeutic Humans Male Prostate/*blood supply/pathology Prostatic Hyperplasia/diagnosis/*therapy Transurethral Resection of Prostate Treatment Outcome Benign prostatic hyperplasia Meta-analysis Prostatic artery embolization Transurethral resection of the prostate PUBLICATION: Not applicable. COMPETING INTERESTS: The authors declare that they have no competing interests. PUBLISHER’S NOTE: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Biomarkers/analysis Humans Male MicroRNAs/*analysis Prostatic Hyperplasia/*diagnosis/metabolism Benign prostatic hyperplasia Diagnosis Prostate cancer Therapy miRNA

Administration Oral Chronic Disease Flowers/physiology Humans Male Medicine Traditional Phytotherapy Plant Extracts/*administration & dosage Pollen/*physiology Prostatic Hyperplasia/drug therapy Prostatitis/drug therapy Treatment Outcome clinical practice efficacy evidence-based complementary and alternative medicine phytotherapy pollen review

Adrenergic alpha-Antagonists Doxazosin Humans Indoles Male Network Meta-Analysis Prostatic Hyperplasia/*drug therapy Quality of Life Sexual Dysfunction Physiological/chemically induced Tamsulosin adverse event alpha adrenergic receptor antagonist benign prostatic hyperplasia

Androgen Antagonists/*pharmacology Biomarkers/urine Humans Inflammation/urine Lower Urinary Tract Symptoms/physiopathology Male Observational Studies as Topic Phytotherapy Plant Extracts/*pharmacology Prostatic Hyperplasia/physiopathology/urine Randomized Controlled Trials as Topic Serenoa Treatment Outcome * Serenoa repens *Luts/bph *Permixon *hexanic extract *meta-analysis *systematic review