Aged Arteries Ejaculation Embolization Therapeutic Humans Lower Urinary Tract Symptoms/*therapy Male Penile Erection Postoperative Complications/etiology Prostate/*blood supply Prostatic Hyperplasia Quality of Life Randomized Controlled Trials as Topic Retreatment/statistics & numerical data Sexual Dysfunction Physiological/etiology *Transurethral Resection of Prostate Treatment Outcome

Humans *Laser Therapy Male *Prostatic Hyperplasia/surgery *Transurethral Resection of Prostate Treatment Outcome bipolar enucleation holmium laser prostate thulium laser

Humans Lasers Solid-State *Learning Curve Male *Postoperative Complications/epidemiology Prostatectomy Prostatic Hyperplasia/complications Treatment Outcome Urinary Bladder Neck Obstruction/etiology *Benign prostatic hyperplasia *Complicaciones *Complications *Curva de aprendizaje *Hiperplasia prostática benigna *HoLEP *Laser *Láser *Prostate *Próstata

Adult Embolization Therapeutic/*adverse effects/methods Humans Lower Urinary Tract Symptoms/*etiology Male Middle Aged Patient Reported Outcome Measures Penile Erection/physiology Prostate/blood supply Prostatic Hyperplasia/*therapy Randomized Controlled Trials as Topic Safety Treatment Outcome Benign prostatic hyperplasia Lower urinary tract symptoms Prostatic artery embolization Systematic review

Aged Drug Therapy Combination Erectile Dysfunction/*drug therapy Humans Male Middle Aged Phosphodiesterase Inhibitors Prostatic Hyperplasia/*drug therapy Tadalafil Tamsulosin Treatment Outcome Vasodilator Agents *benign prostatic hyperplasia *erectile dysfunction *meta-analysis *tadalafil *tamsulosin conflicts of interest with respect to the research authorship and/or publication of this article.

5-alpha Reductase Inhibitors/*administration & dosage Adrenergic alpha-1 Receptor Antagonists/*administration & dosage Drug Therapy Combination Dutasteride/*administration & dosage Erectile Dysfunction/chemically induced/diagnosis Humans Male Prostatic Hyperplasia/diagnosis/*drug therapy/epidemiology Randomized Controlled Trials as Topic/methods Tamsulosin/*administration & dosage Treatment Outcome Benign prostatic hyperplasia Dutasteride Meta-analysis Randomized controlled trials Tamsulosin published studies thus no ethical approval and patient consent are required. CONSENT FOR PUBLICATION: Not applicable. COMPETING INTERESTS: The authors declare that they have no competing interests. PUBLISHER’S NOTE: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Aged Catheterization Humans *Laser Therapy Lower Urinary Tract Symptoms/physiopathology Male Prostate/physiopathology Prostatic Hyperplasia/physiopathology Randomized Controlled Trials as Topic *Transurethral Resection of Prostate Treatment Outcome benign prostatic hyperplasia (BPH) button-type bipolar plasma vaporization (BTPV) lower urinary tract symptoms (LUTS) transurethral resection (TURP)

*Bipolar Disorder China Humans Male Prostatectomy *Prostatic Hyperplasia Quality of Life *Transurethral Resection of Prostate Treatment Outcome Benign prostatic hyperplasia High-risk and senior patients Meta-analysis Systematic review Transurethral bipolar plasmakinetic prostatectomy

Aged Holmium Humans *Laser Therapy Lasers Solid-State Male Postoperative Complications/etiology Prostate/*radiation effects Prostatic Hyperplasia Publication Bias Randomized Controlled Trials as Topic Thulium Treatment Outcome Efficacy Enucleation Holmium laser Meta-analysis Safety Thulium laser

Humans Laparoscopy/*statistics & numerical data Male Margins of Excision Operative Time Prostate/surgery Prostate-Specific Antigen/blood Prostatectomy/*statistics & numerical data Prostatic Hyperplasia Prostatic Neoplasms/blood Robotic Surgical Procedures/*statistics & numerical data Treatment Outcome Urinary Bladder *laparoscopy *prostatectomy *prostatic neoplasms *robotic surgical procedures *urinary bladder neck obstruction

Female Humans Lower Urinary Tract Symptoms/*drug therapy Male Prostatic Hyperplasia/complications/*drug therapy Randomized Controlled Trials as Topic Sexual Dysfunction Physiological Treatment Outcome

Capsules Drugs Chinese Herbal Humans Male Prostatic Hyperplasia/*drug therapy Randomized Controlled Trials as Topic Treatment Outcome Urinary Retention benign prostatic hyperplasia meta-analysis randomized controlled trial systematic review Qianlieshutong Capsules

Blood Transfusion Clinical Trials as Topic Humans Length of Stay Male Minimally Invasive Surgical Procedures Operative Time Prostate Prostatectomy Prostatic Hyperplasia Quality of Life Treatment Outcome Urinary Retention *benign prostatic hyperplasia *laparoscopic *minimally invasive simple prostatectomy *open simple prostatectomy *robotic

Embolization Therapeutic Humans Male Prostate/*blood supply/pathology Prostatic Hyperplasia/diagnosis/*therapy Transurethral Resection of Prostate Treatment Outcome Benign prostatic hyperplasia Meta-analysis Prostatic artery embolization Transurethral resection of the prostate PUBLICATION: Not applicable. COMPETING INTERESTS: The authors declare that they have no competing interests. PUBLISHER’S NOTE: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Humans Male Outcome Assessment Health Care Prostatic Hyperplasia *Transurethral Resection of Prostate/statistics & numerical data Treatment Outcome

Administration Oral Chronic Disease Flowers/physiology Humans Male Medicine Traditional Phytotherapy Plant Extracts/*administration & dosage Pollen/*physiology Prostatic Hyperplasia/drug therapy Prostatitis/drug therapy Treatment Outcome clinical practice efficacy evidence-based complementary and alternative medicine phytotherapy pollen review

Androgen Antagonists/*pharmacology Biomarkers/urine Humans Inflammation/urine Lower Urinary Tract Symptoms/physiopathology Male Observational Studies as Topic Phytotherapy Plant Extracts/*pharmacology Prostatic Hyperplasia/physiopathology/urine Randomized Controlled Trials as Topic Serenoa Treatment Outcome * Serenoa repens *Luts/bph *Permixon *hexanic extract *meta-analysis *systematic review

Humans Length of Stay Male Perioperative Period Prostate/pathology Prostatic Hyperplasia/epidemiology/pathology Randomized Controlled Trials as Topic Saline Solution Transurethral Resection of Prostate/*adverse effects/*economics/standards Treatment Outcome United Kingdom/epidemiology Urethral Stricture/complications Urologic Surgical Procedures *Bph *Benign prostate enlargement *Benign prostate hyperplasia *Cost minimisation analysis *Meta-analysis *TUR syndrome *Turp *TURis *Transurethral resection in saline *Transurethral resection of the prostate

Disease Progression Humans Lower Urinary Tract Symptoms/etiology Male Prostatic Hyperplasia/complications/*drug therapy Risk Factors Time Factors Treatment Outcome Benign prostatic hyperplasia Early treatment Luts Outcomes complications Pharmacological treatment Prostate Surgery

Humans Laser Therapy Male Patient Selection Preoperative Period Prostatic Hyperplasia/complications/physiopathology *Quality of Life Transurethral Resection of Prostate/*adverse effects/methods Treatment Outcome Urinary Bladder Underactive/etiology/*physiopathology *Urodynamics *muscle hypertonia *prostate *prostatic hyperplasia *urethra