Humans Hyperthermia Induced Lower Urinary Tract Symptoms/etiology Male Middle Aged Prostatic Hyperplasia/complications/*therapy Radiofrequency Therapy Randomized Controlled Trials as Topic Steam Treatment Outcome

Humans *Laser Therapy Male *Prostatic Hyperplasia/surgery *Transurethral Resection of Prostate Treatment Outcome bipolar enucleation holmium laser prostate thulium laser

*Electrosurgery Endoscopy Europe Humans Male Prostatectomy Prostatic Hyperplasia Societies Medical Transurethral Resection of Prostate/methods Urology Bpo Benign prostate obstruction Bipolar transurethral resection of the prostate Bladder outlet obstruction Eep Endoscopic enucleation of prostate Systematic review Turp Transurethral enucleation

Humans Lasers Solid-State *Learning Curve Male *Postoperative Complications/epidemiology Prostatectomy Prostatic Hyperplasia/complications Treatment Outcome Urinary Bladder Neck Obstruction/etiology *Benign prostatic hyperplasia *Complicaciones *Complications *Curva de aprendizaje *Hiperplasia prostática benigna *HoLEP *Laser *Láser *Prostate *Próstata

5-alpha Reductase Inhibitors/*administration & dosage Adrenergic alpha-1 Receptor Antagonists/*administration & dosage Drug Therapy Combination Dutasteride/*administration & dosage Erectile Dysfunction/chemically induced/diagnosis Humans Male Prostatic Hyperplasia/diagnosis/*drug therapy/epidemiology Randomized Controlled Trials as Topic/methods Tamsulosin/*administration & dosage Treatment Outcome Benign prostatic hyperplasia Dutasteride Meta-analysis Randomized controlled trials Tamsulosin published studies thus no ethical approval and patient consent are required. CONSENT FOR PUBLICATION: Not applicable. COMPETING INTERESTS: The authors declare that they have no competing interests. PUBLISHER’S NOTE: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Systematic Review Meta-analysis Holmium Laser Enucleation of Prostate Transurethral Resection of Prostate Benign Prostatic Hyperplasia

Administration Oral Fibrinolytic Agents/*administration & dosage Humans Lasers Solid-State Male Prostatic Hyperplasia Risk Factors Antithrombotic Benign prostate hyperplasia (BPH) Holmium laser enucleation of the prostate (HoLEP) Perioperative safety

CT Urography Diagnostic Samples Diagnostics UTUC Upper Tract Urothelial Carcinoma Ureteroscopy

Enucleation Resection of prostate Benign prostatic hyperplasia Meta-analysis

AUC Appropriate Use Criteria Appropriateness Criteria Bladder Cancer Muscle Invasive Bladder Cancer Nonmuscle Invasive Bladder Cancer Surveillance

Aged Holmium Humans *Laser Therapy Lasers Solid-State Male Postoperative Complications/etiology Prostate/*radiation effects Prostatic Hyperplasia Publication Bias Randomized Controlled Trials as Topic Thulium Treatment Outcome Efficacy Enucleation Holmium laser Meta-analysis Safety Thulium laser

Humans Laparoscopy/*statistics & numerical data Male Margins of Excision Operative Time Prostate/surgery Prostate-Specific Antigen/blood Prostatectomy/*statistics & numerical data Prostatic Hyperplasia Prostatic Neoplasms/blood Robotic Surgical Procedures/*statistics & numerical data Treatment Outcome Urinary Bladder *laparoscopy *prostatectomy *prostatic neoplasms *robotic surgical procedures *urinary bladder neck obstruction

Adrenergic alpha-1 Receptor Antagonists/*administration & dosage Adrenergic beta-3 Receptor Agonists/administration & dosage Cholinergic Antagonists/administration & dosage Drug Therapy Combination Humans Lower Urinary Tract Symptoms/*drug therapy Male Phosphodiesterase 5 Inhibitors/*administration & dosage Prostatic Hyperplasia/complications Quality of Life Randomized Controlled Trials as Topic 5-alpha reductase inhibitor Lower urinary tract symptoms alpha blockers anticholinergic: systematic review benign prostatic hyperplasia randomized trials

Holmium Laser Enucleation of Prostate Transurethral Resection of Prostate Benign Prostatic Hyperplasia Meta-analysis

AUC Appropriate Use Criteria Appropriateness Criteria Bladder Cancer CT MRI Muscle-invasive Bladder Cancer Staging Urothelial Carcinoma

Adrenergic alpha-Antagonists Doxazosin Humans Indoles Male Network Meta-Analysis Prostatic Hyperplasia/*drug therapy Quality of Life Sexual Dysfunction Physiological/chemically induced Tamsulosin adverse event alpha adrenergic receptor antagonist benign prostatic hyperplasia

5 alpha-reductase inhibitor benign prostatic hyperplasia meta-analysis

Humans Laser Coagulation Laser Therapy Lasers Solid-State Male Non-Randomized Controlled Trials as Topic/statistics & numerical data Prostatic Hyperplasia/complications Quality of Life Randomized Controlled Trials as Topic/statistics & numerical data *Thulium Transurethral Resection of Prostate Treatment Outcome Ureteral Obstruction/etiology 2-micron Benign prostatic obstruction Plasmakinetic resection of prostate Safety and efficacy Thulium laser VapoResection of the prostate Thulium laser Transurethral resection of the prostate

*Alleles Ethnicity/genetics *Genetic Association Studies *Genetic Predisposition to Disease Genotype Humans Male Odds Ratio *Polymorphism Single Nucleotide Prostate-Specific Antigen/*genetics Prostatic Hyperplasia/*genetics Publication Bias Risk Factors Bph Psa meta-analysis polymorphism

5-alpha Reductase Inhibitors/pharmacology Blood Loss Surgical/*prevention & control Blood Transfusion Dutasteride/*pharmacology Hemoglobins/analysis Humans Male Microcirculation Prospective Studies Prostate Prostatic Hyperplasia Randomized Controlled Trials as Topic Retrospective Studies *Transurethral Resection of Prostate Treatment Outcome Vascular Endothelial Growth Factor A/metabolism Benign prostatic hyperplasia Dutasteride Intraoperative blood loss Meta-analysis Transurethral resection of the prostate