Blood Transfusion/*mortality Combined Modality Therapy Cystectomy/*mortality Humans *Perioperative Care Prognosis Survival Rate Urinary Bladder Neoplasms/pathology/*therapy Bladder cancer Blood transfusion Cystectomy Meta-analysis Oncology Systematic review

Adjuvants Immunologic/therapeutic use BCG Vaccine/therapeutic use Evidence-Based Medicine Humans Neoplasm Invasiveness Neoplasm Recurrence Local/*therapy Treatment Outcome Urinary Bladder Neoplasms/pathology/*therapy Bacillus Calmette-Guerin unresponsive Bladder preservation therapy Bladder sparing Non–muscle-invasive bladder cancer

Adjuvants Immunologic/administration & dosage Administration Intravesical BCG Vaccine/*adverse effects Chondroitin Sulfates/*administration & dosage Cystitis/chemically induced/pathology/*prevention & control Humans Hyaluronic Acid/*administration & dosage Immunotherapy/*adverse effects Randomized Controlled Trials as Topic Urinary Bladder Neoplasms/pathology/*therapy

Adjuvants Immunologic/*therapeutic use Administration Intravesical BCG Vaccine/*therapeutic use Carcinoma Transitional Cell/pathology/*therapy Cystoscopy Female Humans Male Multivariate Analysis Muscle Smooth/*pathology Neoplasm Invasiveness Neoplasm Recurrence Local/*epidemiology Proportional Hazards Models Sex Factors Survival Rate Urinary Bladder Neoplasms/pathology/*therapy *Urologic Surgical Procedures Bladder cancer Gender differences Local recurrence Meta-analysis Transurethral resection of bladder tumor

Chemoradiotherapy Adjuvant Combined Modality Therapy Cystectomy/*methods Disease-Free Survival Humans Muscles/pathology Neoadjuvant Therapy Neoplasm Invasiveness Treatment Outcome Urinary Bladder Neoplasms/pathology/*therapy Bladder cancer Radical cystectomy Trimodal therapy

Antineoplastic Agents/*therapeutic use Carcinoma Transitional Cell/pathology/*therapy Chemotherapy Adjuvant Cystectomy Cystoscopy Humans Lymph Node Excision Muscle Smooth/*pathology *Neoadjuvant Therapy Neoplasm Invasiveness *Organ Sparing Treatments Progression-Free Survival Proportional Hazards Models *Radiotherapy Adjuvant Survival Rate Urinary Bladder Neoplasms/pathology/*therapy Bladder preserving Cancer Muscle invasive Radical cystectomy Trimodal

Adjuvants Immunologic/*administration & dosage Administration Intravesical Antineoplastic Agents/therapeutic use BCG Vaccine/*administration & dosage Humans Instillation Drug Randomized Controlled Trials as Topic Urinary Bladder Neoplasms/pathology/*therapy Bacillus Calmette-Guerin Maintenance therapy Non-muscle-invasive bladder cancer Progression Recurrence