Anticoagulants Humans Male Platelet Aggregation Inhibitors Postoperative Hemorrhage/chemically induced Prostatic Hyperplasia *Transurethral Resection of Prostate

Individual International Prostate Symptom Score Benign prostatic hyperplasia Meta-analysis

Alpha blocker and phosphodiesterase 5 inhibitor Alpha-blocker monotherapy benign prostate hyperplasia systematic review meta-analysis

Aged Aged 80 and over Humans Male Middle Aged Outcome Assessment Health Care Plant Extracts/administration & dosage Prostatic Hyperplasia/*drug therapy Serenoa Tamsulosin/administration & dosage Urological Agents/administration & dosage *Serenoa repens *benign prostatic hyperplasia *meta-analysis *randomized controlled trials *tamsulosin conflicts of interest with respect to the research authorship and/or publication of this article.

Adrenergic alpha-Antagonists/*administration & dosage/pharmacology Drug Interactions Drug Therapy Combination Erectile Dysfunction/complications/*drug therapy/physiopathology Hemodynamics/*drug effects Humans Lower Urinary Tract Symptoms/complications/*drug therapy/physiopathology Male Phosphodiesterase 5 Inhibitors/*administration & dosage/pharmacology Prostatic Hyperplasia/complications/*drug therapy/physiopathology Randomized Controlled Trials as Topic Alpha blocker Benign prostatic hyperplasia Erectile dysfunction Hemodynamic interaction Luts Phosphodiesterase-5 inhibitors

Adult Embolization Therapeutic/*adverse effects/methods Humans Lower Urinary Tract Symptoms/*etiology Male Middle Aged Patient Reported Outcome Measures Penile Erection/physiology Prostate/blood supply Prostatic Hyperplasia/*therapy Randomized Controlled Trials as Topic Safety Treatment Outcome Benign prostatic hyperplasia Lower urinary tract symptoms Prostatic artery embolization Systematic review

Aged Drug Therapy Combination Erectile Dysfunction/*drug therapy Humans Male Middle Aged Phosphodiesterase Inhibitors Prostatic Hyperplasia/*drug therapy Tadalafil Tamsulosin Treatment Outcome Vasodilator Agents *benign prostatic hyperplasia *erectile dysfunction *meta-analysis *tadalafil *tamsulosin conflicts of interest with respect to the research authorship and/or publication of this article.

5-alpha Reductase Inhibitors/*administration & dosage Adrenergic alpha-1 Receptor Antagonists/*administration & dosage Drug Therapy Combination Dutasteride/*administration & dosage Erectile Dysfunction/chemically induced/diagnosis Humans Male Prostatic Hyperplasia/diagnosis/*drug therapy/epidemiology Randomized Controlled Trials as Topic/methods Tamsulosin/*administration & dosage Treatment Outcome Benign prostatic hyperplasia Dutasteride Meta-analysis Randomized controlled trials Tamsulosin published studies thus no ethical approval and patient consent are required. CONSENT FOR PUBLICATION: Not applicable. COMPETING INTERESTS: The authors declare that they have no competing interests. PUBLISHER’S NOTE: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Bladder Cancer Checkpoint Inhibitors Chemotherapy Immunotherapy Urothelial Cancer

Photoselective vaporization benign prostate hyperplasia meta-analysis

Oral antithrombotic drugs benign prostate hyperplasia

Adjuvant Chemotherapy Bladder-sparing Chemoradiation Enhanced Recovery after Surgery Muscle-invasive Bladder Cancer Neoadjuvant Chemotherapy Radical Cystectomy Transurethral Resection of Bladder Tumor Trimodal Urothelial Carcinoma of Bladder Variant Histology

Anticoagulants Blood Transfusion *Deprescriptions Dysuria/epidemiology Humans Laser Therapy Male Operative Time Postoperative Complications/epidemiology Prostatic Hyperplasia Reoperation Transurethral Resection of Prostate Urethral Stricture/epidemiology Urinary Tract Infections/epidemiology Anticoagulant Benign prostate hyperplasia (BPH) Lower urinary tract symptom (LUTS) Photoselective vaporization (PVP)

Administration Oral Fibrinolytic Agents/*administration & dosage Humans Lasers Solid-State Male Prostatic Hyperplasia Risk Factors Antithrombotic Benign prostate hyperplasia (BPH) Holmium laser enucleation of the prostate (HoLEP) Perioperative safety

Aged Catheterization Humans *Laser Therapy Lower Urinary Tract Symptoms/physiopathology Male Prostate/physiopathology Prostatic Hyperplasia/physiopathology Randomized Controlled Trials as Topic *Transurethral Resection of Prostate Treatment Outcome benign prostatic hyperplasia (BPH) button-type bipolar plasma vaporization (BTPV) lower urinary tract symptoms (LUTS) transurethral resection (TURP)

Bladder Cancer Chemotherapy Cystectomy Immune Checkpoint Inhibitors

*Bipolar Disorder China Humans Male Prostatectomy *Prostatic Hyperplasia Quality of Life *Transurethral Resection of Prostate Treatment Outcome Benign prostatic hyperplasia High-risk and senior patients Meta-analysis Systematic review Transurethral bipolar plasmakinetic prostatectomy

Phosphodiesterase type 5 inhibitor Lower urinary tract symptoms Benign prostatic hyperplasia Meta-analysis

Adrenergic alpha-1 Receptor Antagonists/*administration & dosage Adrenergic beta-3 Receptor Agonists/administration & dosage Cholinergic Antagonists/administration & dosage Drug Therapy Combination Humans Lower Urinary Tract Symptoms/*drug therapy Male Phosphodiesterase 5 Inhibitors/*administration & dosage Prostatic Hyperplasia/complications Quality of Life Randomized Controlled Trials as Topic 5-alpha reductase inhibitor Lower urinary tract symptoms alpha blockers anticholinergic: systematic review benign prostatic hyperplasia randomized trials

Photoselective green light laser vaporisation traditional transurethral resection benign prostate hyperplasia meta-analysis