Animals Humans *Lower Urinary Tract Symptoms/drug therapy Male Prostatic Hyperplasia/therapy Urinary Bladder Overactive/complications *Urothelium/physiopathology

Animals Dietary Supplements Humans Nitroso Compounds/*administration & dosage Risk Factors Urinary Bladder Neoplasms/*diagnosis Bladder Dietary Neoplasms Nitrate Nitrite Nitrosamines Organic chemicals

Animals *Cheese Cohort Studies Dairy Products Diet Humans Milk Risk Factors *Urinary Bladder Neoplasms/epidemiology/etiology Yogurt

Animals Body Mass Index Case-Control Studies Cohort Studies Dairy Products/*statistics & numerical data Diet/methods Educational Status Feeding Behavior Female Humans Male Milk/*statistics & numerical data Risk Factors Smoking/epidemiology Urinary Bladder Neoplasms/*epidemiology

Animals Biological Availability Clinical Trials as Topic Flavonoids/pharmacology/*therapeutic use Flavonols/pharmacology/*therapeutic use Humans Inhibitory Concentration 50 Kaempferols/pharmacology/*therapeutic use Male Models Animal Prostatic Neoplasms/*drug therapy Urinary Bladder Neoplasms/*drug therapy bladder cancer fisetin kaempferol myricetin prostate cancer

Animals Diabetes Mellitus/*physiopathology Disease Progression Humans Obesity/*complications Urinary Bladder Neoplasms/etiology/*pathology all-cause mortality cancer specific mortality diabetes disease recurrence obesity overweight urinary bladder cancer commercial or financial relationships that could be construed as a potential conflict of interest.

Adolescent Adult Aged Aged 80 and over Animals Cultured Milk Products *Dairy Products *Diet Dietary Fats/administration & dosage *Feeding Behavior Female Humans Male Middle Aged Milk *Urinary Bladder Neoplasms/etiology/prevention & control Young Adult dairy products fermented dairy products whole milk bladder cancer meta-analysis systematic review

Biomarkers Tumor/*urine Fibronectins/*urine Humans Prognosis Urinary Bladder Neoplasms/*diagnosis/urine Biomarker Bladder cancer Diagnosis Meta-analysis Urine fibronectin standards of institutional and international research committee this article is based on previous published studies thus it does not contain any studies with human participants or animals. CONSENT FOR PUBLICATION: Not applicable. COMPETING INTERESTS: The authors declare that they have no competing interests. PUBLISHER’S NOTE: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Animals Cattle Diet/*adverse effects *Evidence-Based Medicine Food Preserved/*adverse effects Humans Incidence Meat/*adverse effects Meat Products/*adverse effects Reproducibility of Results Risk Factors Sheep Domestic Sus scrofa Urinary Bladder Neoplasms/epidemiology/*etiology Bladder cancer Dose–response Meta-analysis Processed meat Red meat