*Bipolar Disorder China Humans Male Prostatectomy *Prostatic Hyperplasia Quality of Life *Transurethral Resection of Prostate Treatment Outcome Benign prostatic hyperplasia High-risk and senior patients Meta-analysis Systematic review Transurethral bipolar plasmakinetic prostatectomy

Aged Holmium Humans *Laser Therapy Lasers Solid-State Male Postoperative Complications/etiology Prostate/*radiation effects Prostatic Hyperplasia Publication Bias Randomized Controlled Trials as Topic Thulium Treatment Outcome Efficacy Enucleation Holmium laser Meta-analysis Safety Thulium laser

Humans Lower Urinary Tract Symptoms Male Postoperative Complications/*etiology Prostatic Hyperplasia Randomized Controlled Trials as Topic Sexual Dysfunction Physiological/*etiology Urologic Surgical Procedures Male/*adverse effects

Humans Laparoscopy/*statistics & numerical data Male Margins of Excision Operative Time Prostate/surgery Prostate-Specific Antigen/blood Prostatectomy/*statistics & numerical data Prostatic Hyperplasia Prostatic Neoplasms/blood Robotic Surgical Procedures/*statistics & numerical data Treatment Outcome Urinary Bladder *laparoscopy *prostatectomy *prostatic neoplasms *robotic surgical procedures *urinary bladder neck obstruction

Female Humans Lower Urinary Tract Symptoms/*drug therapy Male Prostatic Hyperplasia/complications/*drug therapy Randomized Controlled Trials as Topic Sexual Dysfunction Physiological Treatment Outcome

Adrenergic alpha-1 Receptor Antagonists/*administration & dosage Adrenergic beta-3 Receptor Agonists/administration & dosage Cholinergic Antagonists/administration & dosage Drug Therapy Combination Humans Lower Urinary Tract Symptoms/*drug therapy Male Phosphodiesterase 5 Inhibitors/*administration & dosage Prostatic Hyperplasia/complications Quality of Life Randomized Controlled Trials as Topic 5-alpha reductase inhibitor Lower urinary tract symptoms alpha blockers anticholinergic: systematic review benign prostatic hyperplasia randomized trials

Capsules Drugs Chinese Herbal Humans Male Prostatic Hyperplasia/*drug therapy Randomized Controlled Trials as Topic Treatment Outcome Urinary Retention benign prostatic hyperplasia meta-analysis randomized controlled trial systematic review Qianlieshutong Capsules

Blood Transfusion Clinical Trials as Topic Humans Length of Stay Male Minimally Invasive Surgical Procedures Operative Time Prostate Prostatectomy Prostatic Hyperplasia Quality of Life Treatment Outcome Urinary Retention *benign prostatic hyperplasia *laparoscopic *minimally invasive simple prostatectomy *open simple prostatectomy *robotic

Aged Humans Lower Urinary Tract Symptoms/*etiology Male Prostatic Hyperplasia Transurethral Resection of Prostate Urethra/physiopathology

Embolization Therapeutic Humans Male Prostate/*blood supply/pathology Prostatic Hyperplasia/diagnosis/*therapy Transurethral Resection of Prostate Treatment Outcome Benign prostatic hyperplasia Meta-analysis Prostatic artery embolization Transurethral resection of the prostate PUBLICATION: Not applicable. COMPETING INTERESTS: The authors declare that they have no competing interests. PUBLISHER’S NOTE: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Aged Aged 80 and over Ejaculation Humans Lower Urinary Tract Symptoms/etiology Male Middle Aged Organ Size Penile Erection Prostate/pathology Prostatic Hyperplasia/complications Quality of Life Retreatment/statistics & numerical data Robotic Surgical Procedures Surgery Computer-Assisted/methods Transurethral Resection of Prostate *Water

Humans Male Outcome Assessment Health Care Prostatic Hyperplasia *Transurethral Resection of Prostate/statistics & numerical data Treatment Outcome

Biomarkers/analysis Humans Male MicroRNAs/*analysis Prostatic Hyperplasia/*diagnosis/metabolism Benign prostatic hyperplasia Diagnosis Prostate cancer Therapy miRNA

Humans Male *Prostatic Hyperplasia

Administration Oral Chronic Disease Flowers/physiology Humans Male Medicine Traditional Phytotherapy Plant Extracts/*administration & dosage Pollen/*physiology Prostatic Hyperplasia/drug therapy Prostatitis/drug therapy Treatment Outcome clinical practice efficacy evidence-based complementary and alternative medicine phytotherapy pollen review

Adrenergic alpha-Antagonists Doxazosin Humans Indoles Male Network Meta-Analysis Prostatic Hyperplasia/*drug therapy Quality of Life Sexual Dysfunction Physiological/chemically induced Tamsulosin adverse event alpha adrenergic receptor antagonist benign prostatic hyperplasia

Androgen Antagonists/*pharmacology Biomarkers/urine Humans Inflammation/urine Lower Urinary Tract Symptoms/physiopathology Male Observational Studies as Topic Phytotherapy Plant Extracts/*pharmacology Prostatic Hyperplasia/physiopathology/urine Randomized Controlled Trials as Topic Serenoa Treatment Outcome * Serenoa repens *Luts/bph *Permixon *hexanic extract *meta-analysis *systematic review

Humans Length of Stay Male Perioperative Period Prostate/pathology Prostatic Hyperplasia/epidemiology/pathology Randomized Controlled Trials as Topic Saline Solution Transurethral Resection of Prostate/*adverse effects/*economics/standards Treatment Outcome United Kingdom/epidemiology Urethral Stricture/complications Urologic Surgical Procedures *Bph *Benign prostate enlargement *Benign prostate hyperplasia *Cost minimisation analysis *Meta-analysis *TUR syndrome *Turp *TURis *Transurethral resection in saline *Transurethral resection of the prostate

Humans Lower Urinary Tract Symptoms Male Phosphodiesterase 5 Inhibitors/administration & dosage/adverse effects Placebos Prostatic Hyperplasia/complications/*etiology Quality of Life Regression Analysis Severity of Illness Index Lower urinary tract symptoms Meta-analysis Phosphodiesterase 5 inhibitor Placebo Prostatic hyperplasia

Humans Male Postoperative Complications Prostatic Hyperplasia Randomized Controlled Trials as Topic *Transurethral Resection of Prostate/methods