首页良性前列腺增生治疗及预后证据详情

The impact of surgery for lower urinary tract symptoms/benign prostatic enlargement on both erectile and ejaculatory function: a systematic review

原文:2019年 发布于 Int J Impot Res 31卷 第5期 319-327 浏览量:626次 原文链接

作者: Verze P. Califano G. Sokolakis I. Russo G. I. Hatzichristodoulou G. Musi G. Creta M.

作者单位: Department of Neurosciences, reproductive sciences and odontostomatology-Urology Unit, University Federico II of Naples, Naples, Italy. pverze@gmail.com. Department of Neurosciences, reproductive sciences and odontostomatology-Urology Unit, University Federico II of Naples, Naples, Italy. Department of Urology and Pediatric Urology, Julius-Maximilians University of Würzburg, Würzburg, Germany. Urology Section, University of Catania, Catania, Italy. Urology Department, Istituto Europeo di Oncologia (I.E.O.), Milan, Italy.

归属分类: 良性前列腺增生治疗及预后证据

DOI: 10.1038/s41443-019-0140-0

关键词: Humans Lower Urinary Tract Symptoms Male Postoperative Complications/*etiology Prostatic Hyperplasia Randomized Controlled Trials as Topic Sexual Dysfunction Physiological/*etiology Urologic Surgical Procedures Male/*adverse effects

文献简介

We performed a systematic review of studies evaluating the impact of surgery for lower urinary tract symptoms suggestive of benign prostate enlargement (LUTS/BPE) on both erectile and ejaculatory functions. In June 2018, we searched for randomized controlled trials (RCTs) published between 1998 and 2018 in which both functions were assessed using questionnaires. Overall, 15 studies were identified. Pre-operatively, mean International Index of Erectile Function -5 (IIEF-5) and mean IIEF-Erectile Function (EF) scores ranged from 13.3 to 20.8, and from 13.7 to 22.3, respectively. At follow-up evaluations, mean IIEF-5 and mean IIEF-EF scores did not significantly vary (13.4 to 20.7 and 14.4 to 24.3, respectively). Mean baseline Male Sexual Health Questionnaire- Ejaculatory Disease function score at baseline and follow-up evaluations ranged from 8.7 to 10.6, and from 4.9 to 11.9, respectively. Ejaculatory function significantly worsened in three studies after transurethral resection of the prostate and significantly improved in 2 studies after prostate urethral lift implant. In conclusions, available RCTs evaluating both erectile and ejaculatory functions after surgical procedures for LUTS/BPE fail to demonstrate significant variations in terms of erectile function scores while providing significant variations of ejaculatory function scores that are heterogeneous depending on the procedure adopted.

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