首页良性前列腺增生治疗及预后证据详情

Systematic review of lower urinary tract symptoms/benign prostatic hyperplasia surgical treatments on men's ejaculatory function: Time for a bespoke approach?

原文:2016年 发布于 Int J Urol 23卷 第1期 22-35 浏览量:1052次 原文链接

作者: Marra G. Sturch P. Oderda M. Tabatabaei S. Muir G. Gontero P.

作者单位: Urology Clinic, Città della Salute e della Scienza, University of Turin, Turin, Italy. Department of Urology, King's College Hospital, London, UK. Department of Urology, Massachusetts General Hospital, Boston, MA, USA.

归属分类: 良性前列腺增生治疗及预后证据

DOI: 10.1111/iju.12866

关键词: *Ejaculation Humans Male Prostatic Hyperplasia/complications Prostatism/etiology Randomized Controlled Trials as Topic Sexual Dysfunction Physiological/*etiology/physiopathology Urologic Surgical Procedures Male/*adverse effects benign prostatic hyperplasia decreased ejaculation ejaculatory dysfunction lower urinary tract symptoms painful ejaculation retrograde ejaculation

文献简介

Although ejaculatory dysfunction is common for patients undergoing benign prostatic hyperplasia surgery, no clear evidence is present to counsel men seeking to preserve ejaculation. Our aim was to evaluate ejaculatory dysfunction in relation to benign prostatic hyperplasia surgery. We carried out a web and manual search using MEDLINE and Embase including randomized controlled trials reporting ejaculatory dysfunction after benign prostatic hyperplasia surgery: 42 randomized controlled trials comprising a total of 3857 patients were included. Only one study had ejaculatory dysfunction as a primary outcome, and just 10 evaluated ejaculatory dysfunction before and after surgery. The definition of ejaculatory dysfunction was not standardized. Similarly, just seven studies used internationally validated questionnaires to address ejaculatory dysfunction. The reported rates of ejaculatory dysfunction after resectional electrosurgery, laser procedures, coagulation, ablation and implant techniques were assessed and compared. Transurethral resection of the prostate and recent laser procedures including holmium, thulium and GreenLight cause similar rates of ejaculatory dysfunction, occurring in almost three out of four to five men. Although providing less symptomatic benefit compared with transurethral resection of the prostate, transurethral incision of the prostate, transurethral needle ablation and transurethral microwave thermotherapy should be considered for men aiming to maintain normal ejaculation. UroLift is also a recent promising option for this category of patients. The vast majority of studies reporting ejaculatory dysfunction after benign prostatic hyperplasia surgery used poor methodology to investigate this complication. Future studies able to address clear hypothesis and considering ejaculatory dysfunction anatomical and pathophysiological features are required to develop ejaculation preserving techniques and to increase the evidence to counsel men aiming to preserve ejaculation.

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