bladder cancer checkpoint inhibitors chemotherapy immunotherapy radical cystectomy design of the study in the collection analyses or interpretation of data in the writing of the manuscript or in the decision to publish the results.

Cisplatin/adverse effects Humans *Immunotherapy/adverse effects/methods *Muscles/pathology *Neoadjuvant Therapy/adverse effects Neoplasm Staging *Urinary Bladder Neoplasms/drug therapy/pathology/therapy chemoimmunotherapy immunotherapy meta-analysis muscle-invasive bladder cancer (MIBC) neoadjuvant commercial or financial relationships that could be construed as a potential conflict of interest.

Humans *Urinary Bladder Neoplasms/surgery/pathology Neoplasm Recurrence Local/pathology Cystectomy/methods Cystoscopy/methods Light #BladderCancer #blcsm #uroonc blue light non-muscle-invasive bladder cancer photodynamic diagnosis transurethral resection of the bladder white light

Humans *Neoplasm Recurrence Local/drug therapy *Urinary Bladder Neoplasms/pathology Infusions Intra-Arterial Chemotherapy Adjuvant Adverse Reactions bladder cancer intra-arterial chemotherapy meta-analysis prognosis

Humans Magnetic Resonance Imaging *Multiparametric Magnetic Resonance Imaging Muscles Prospective Studies Urinary Bladder *Urinary Bladder Neoplasms/diagnostic imaging Bladder cancer Meta-analysis Muscle invasion Vesical imaging-reporting and data system

Bcg Bacillus Calmette–Guérin Nmibc bladder cancer checkpoint inhibition therapy nadofaragene firadenovec non muscle invasive oncolytic viruses

Female Gene Expression Profiling Gene Regulatory Networks Humans Male Muscles Neoplasm Invasiveness Prognosis *Urinary Bladder Neoplasms/genetics/metabolism rab GTP-Binding Proteins/genetics/metabolism Bladder cancer Gene expression Muscle-invasive bladder cancer Urothelial cancer

Bladder cancer neoadjuvant chemotherapy radical cystectomy systematic review variant histology urothelial cancer

Humans Female Male *Urinary Bladder Neoplasms/etiology/microbiology RNA Ribosomal 16S/genetics Urinary Bladder/microbiology *Microbiota/genetics Bacteria/genetics Bladder cancer Gender Urinary microbiota Uropathogens of interest.

biomarker bladder cancer diagnosis extracellular vesicle miRNAs pellet sediment supernatant urine

Artificial Intelligence Humans Muscles/pathology ROC Curve Sensitivity and Specificity *Urinary Bladder Neoplasms/diagnostic imaging/pathology Bladder cancer Meta-analysis Muscle invasive Radiomics Staging Systematic review

adjuvant immune checkpoint inhibitors muscle-invasive bladder cancer neoadjuvant

Cystectomy/*methods Electrosurgery/*methods Humans Neoplasm Invasiveness Urethra Urinary Bladder Neoplasms/pathology/*surgery Bipolar Meta-analysis Monopolar Non-muscle invasive bladder cancer Transurethral resection

Cohort Studies Diet Female Humans Male Prospective Studies Risk Factors Thiamine *Urinary Bladder Neoplasms/epidemiology/etiology/prevention & control Vitamin A Vitamin B 12 *Vitamin B Complex B group vitamins Bladder cancer Nutritional oncology Pooled cohort analysis

fluorescence in situ hybridization meta-analysis non-muscle invasive bladder cancer surveillance needs to disclose.

*Antineoplastic Agents/adverse effects *Carcinoma Transitional Cell/drug therapy Humans Mutation Receptor ErbB-2 Trastuzumab/adverse effects *Urinary Bladder Neoplasms/drug therapy Erbb2 Her2 Metastatic bladder cancer Metastatic urothelial cancer Targeted treatment

Biomarkers Humans Inflammation Prognosis Proportional Hazards Models *Urinary Bladder Neoplasms bladder cancer meta-analysis survival systemic immune-inflammation index commercial or financial relationships that could be construed as a potential conflict of interest.

Bladder cancer Cytology Hematuria Mcm5 Urinary markers to the content of this report.

*Cystectomy/adverse effects Humans Postoperative Complications/epidemiology/etiology Prospective Studies Retrospective Studies *Robotic Surgical Procedures/adverse effects *Robotics Treatment Outcome *Urinary Bladder Neoplasms/surgery Bladder cancer Intracorporeal Meta-analysis Radical cystectomy Robot-assisted

bladder cancer meta-analysis smoking cessation survival systematic review