Anticoagulants Blood Transfusion *Deprescriptions Dysuria/epidemiology Humans Laser Therapy Male Operative Time Postoperative Complications/epidemiology Prostatic Hyperplasia Reoperation Transurethral Resection of Prostate Urethral Stricture/epidemiology Urinary Tract Infections/epidemiology Anticoagulant Benign prostate hyperplasia (BPH) Lower urinary tract symptom (LUTS) Photoselective vaporization (PVP)

Administration Oral Fibrinolytic Agents/*administration & dosage Humans Lasers Solid-State Male Prostatic Hyperplasia Risk Factors Antithrombotic Benign prostate hyperplasia (BPH) Holmium laser enucleation of the prostate (HoLEP) Perioperative safety

Aged Catheterization Humans *Laser Therapy Lower Urinary Tract Symptoms/physiopathology Male Prostate/physiopathology Prostatic Hyperplasia/physiopathology Randomized Controlled Trials as Topic *Transurethral Resection of Prostate Treatment Outcome benign prostatic hyperplasia (BPH) button-type bipolar plasma vaporization (BTPV) lower urinary tract symptoms (LUTS) transurethral resection (TURP)

*Bipolar Disorder China Humans Male Prostatectomy *Prostatic Hyperplasia Quality of Life *Transurethral Resection of Prostate Treatment Outcome Benign prostatic hyperplasia High-risk and senior patients Meta-analysis Systematic review Transurethral bipolar plasmakinetic prostatectomy

Enucleation Resection of prostate Benign prostatic hyperplasia Meta-analysis

Aged Holmium Humans *Laser Therapy Lasers Solid-State Male Postoperative Complications/etiology Prostate/*radiation effects Prostatic Hyperplasia Publication Bias Randomized Controlled Trials as Topic Thulium Treatment Outcome Efficacy Enucleation Holmium laser Meta-analysis Safety Thulium laser

Benign prostate hyperplasia metabolic syndrome meta-analysis

Humans Laparoscopy/*statistics & numerical data Male Margins of Excision Operative Time Prostate/surgery Prostate-Specific Antigen/blood Prostatectomy/*statistics & numerical data Prostatic Hyperplasia Prostatic Neoplasms/blood Robotic Surgical Procedures/*statistics & numerical data Treatment Outcome Urinary Bladder *laparoscopy *prostatectomy *prostatic neoplasms *robotic surgical procedures *urinary bladder neck obstruction

Prostate artery embolisationl benign prostatic hyperplasia systematic review meta-analysis

Blood Transfusion Clinical Trials as Topic Humans Length of Stay Male Minimally Invasive Surgical Procedures Operative Time Prostate Prostatectomy Prostatic Hyperplasia Quality of Life Treatment Outcome Urinary Retention *benign prostatic hyperplasia *laparoscopic *minimally invasive simple prostatectomy *open simple prostatectomy *robotic

Photoselective green light laser vaporisation traditional transurethral resection benign prostate hyperplasia meta-analysis

Aged Humans Lower Urinary Tract Symptoms/*etiology Male Prostatic Hyperplasia Transurethral Resection of Prostate Urethra/physiopathology

Embolization Therapeutic Humans Male Prostate/*blood supply/pathology Prostatic Hyperplasia/diagnosis/*therapy Transurethral Resection of Prostate Treatment Outcome Benign prostatic hyperplasia Meta-analysis Prostatic artery embolization Transurethral resection of the prostate PUBLICATION: Not applicable. COMPETING INTERESTS: The authors declare that they have no competing interests. PUBLISHER’S NOTE: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Aged Aged 80 and over Ejaculation Humans Lower Urinary Tract Symptoms/etiology Male Middle Aged Organ Size Penile Erection Prostate/pathology Prostatic Hyperplasia/complications Quality of Life Retreatment/statistics & numerical data Robotic Surgical Procedures Surgery Computer-Assisted/methods Transurethral Resection of Prostate *Water

Humans Male Outcome Assessment Health Care Prostatic Hyperplasia *Transurethral Resection of Prostate/statistics & numerical data Treatment Outcome

Biomarkers/analysis Humans Male MicroRNAs/*analysis Prostatic Hyperplasia/*diagnosis/metabolism Benign prostatic hyperplasia Diagnosis Prostate cancer Therapy miRNA

Holmium Laser Enucleation of Prostate Transurethral Resection of Prostate Benign Prostatic Hyperplasia Meta-analysis

Humans Length of Stay Male Perioperative Period Prostate/pathology Prostatic Hyperplasia/epidemiology/pathology Randomized Controlled Trials as Topic Saline Solution Transurethral Resection of Prostate/*adverse effects/*economics/standards Treatment Outcome United Kingdom/epidemiology Urethral Stricture/complications Urologic Surgical Procedures *Bph *Benign prostate enlargement *Benign prostate hyperplasia *Cost minimisation analysis *Meta-analysis *TUR syndrome *Turp *TURis *Transurethral resection in saline *Transurethral resection of the prostate

Humans Male Postoperative Complications Prostatic Hyperplasia Randomized Controlled Trials as Topic *Transurethral Resection of Prostate/methods

Disease Progression Humans Lower Urinary Tract Symptoms/etiology Male Prostatic Hyperplasia/complications/*drug therapy Risk Factors Time Factors Treatment Outcome Benign prostatic hyperplasia Early treatment Luts Outcomes complications Pharmacological treatment Prostate Surgery