首页良性前列腺增生治疗及预后证据详情

Shedding light on polypragmasy of pain after transurethral prostate surgery procedures: a systematic review and meta-analysis

原文:2021年 发布于 World J Urol 39卷 第10期 3711-3720 浏览量:1487次 原文链接

作者: Wroclawski M. L. Castellani D. Heldwein F. L. Teles S. B. Cha J. D. Zhao H. Herrmann T. Chan V. W. Teoh J. Y.

作者单位: Hospital Israelita Albert Einstein, São Paulo, Brazil. urologia.marcelo@gmail.com. BP-a Beneficência Portuguesa de São Paulo, São Paulo, Brazil. urologia.marcelo@gmail.com. Faculdade de Medicina Do ABC, Santo André, Brazil. urologia.marcelo@gmail.com. Urology Division, Azienda Ospedaliero-Universitaria Ospedali Riuniti Di Ancona, Università Politecnica Delle Marche, Ancona, Italy. Department of Urology, Federal University of Santa Catarina, Florianópolis, Brazil. Hospital Israelita Albert Einstein, São Paulo, Brazil. S.H. Ho Urology Centre, Department of Surgery, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China. Department of Urology, Spital Thurgau AG, Frauenfeld, Switzerland. Department of Urology, Hanover Medical School (MHH), Hanover, Germany. School of Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, UK.

归属分类: 良性前列腺增生治疗及预后证据

DOI: 10.1007/s00345-021-03678-6

关键词: Humans Incidence Male Pain Postoperative/*epidemiology Pelvic Pain/*epidemiology Prostatic Hyperplasia Transurethral Resection of Prostate/*adverse effects Dysuria Pain Prostate Prostatic hyperplasia Transurethral resection of prostate Urological surgical procedures

文献简介

PURPOSE AND OBJECTIVE: To evaluate and compare the incidences of post-operative pelvic pain (PPP) in patients undergoing ablation, enucleation and conventional transurethral resection of the prostate (TURP). METHODS: A systematic review and meta-analysis was conducted according to the PRISMA guidelines. Using MEDLINE via PubMed and Cochrane CENTRAL, randomised control trials (RCTs) and observational studies reporting PPP rates post-ablation, enucleation or TURP were identified. The risk of biases (RoB) in RCTs and observation studies were assessed using the Cochrane RoB1.0 tool and the Newcastle-Ottawa Scale, respectively. RESULTS: 62 studies were included for qualitative analysis, while 51 of them reported number of patients with PPP post-intervention. Three observational studies and 13 RCTs compared the rates of PPP in patients undergoing ablation, enucleation or TURP. The most reported types of PPP are dysuria, abdominal pain and irritative symptoms. The pooled incidence of PPP at 1-month follow-up in patients undergoing ablation, enucleation and TURP were 0.15 (95% CI 0.10-0.22), 0.09 (95% CI 0.04-0.19 and 0.10 (95% CI 0.06-0.15), respectively. PPP is no longer prevalent at 3-months and onwards post-operatively. Ablation is associated with a higher risk of PPP than enucleation (RR 2.19, 95% CI 1.04-4.62) and TURP (RR 2.40, 95% CI 1.03-5.62) in observational studies but not RCTs; and there were no significant differences in the rates of PPP upon comparison of other modalities. CONCLUSION: PPP is common after transurethral benign prostatic hyperplasia surgery. Patients undergoing ablation had a higher rate of post-intervention PPP than those undergoing enucleation and TURP in observational studies.

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