首页良性前列腺增生治疗及预后证据详情

Bladder neck stenosis after transurethral prostate surgery: a systematic review and meta-analysis

原文:2021年 发布于 World J Urol 39卷 第11期 4073-4083 浏览量:911次 原文链接

作者: Castellani D. Wroclawski M. L. Pirola G. M. Gauhar V. Rubilotta E. Chan V. W. Cheng B. K. Gubbiotti M. Galosi A. B. Herrmann T. R. W. Teoh J. Y.

作者单位: Department of Urology, University Hospital "Ospedali Riuniti" and Polytechnic University of Marche Region, via Conca 71, 60126, Ancona, Italy. Hospital Israelita Albert Einstein, BP-A Beneficência Portuguesa de São Paulo, São Paulo, Brazil. Faculdade de Medicina do ABC, Santo André, Brazil. Department of Urology, San Donato Hospital, Arezzo, Italy. Ng Teng Fong General Hospital (NUHS), Singapore, Singapore. Department of Urology, A.O.U.I. Verona University, Verona, Italy. School of Medicine, Faculty of Medicine and Health, University of Leeds, Leeds, UK. Department of Surgery, United Christian Hospital, Hong Kong, China. Department of Urology, Spital Thurgau AG (STGAG), Frauenfeld, Switzerland. S.H. Ho Urology Centre, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China. jeremyteoh@surgery.cuhk.edu.hk.

归属分类: 良性前列腺增生治疗及预后证据

DOI: 10.1007/s00345-021-03718-1

关键词: Constriction Pathologic Humans Incidence Male Postoperative Complications/*epidemiology Prostatic Hyperplasia *Transurethral Resection of Prostate Urinary Bladder Neck Obstruction/*epidemiology Benign prostatic hyperplasia Laser therapy Postoperative complications Prostatectomy Transurethral Transurethral resection of prostate Urinary bladder neck obstruction

文献简介

PURPOSE: Bladder neck stenosis (BNS) is a long-term complication of surgical procedures for benign prostatic hyperplasia (BPH). We performed a systematic literature review and a meta-analysis of the incidence of BNS after transurethral procedures for BPH. METHODS: We performed a systemic literature review using MEDLINE, EMBASE, and Cochrane Central Controlled Register of Trials. We accepted only randomized trials comparing transurethral resection of the prostate (TURP) vs. other transurethral surgery for BPH that were grouped in Ablation vs. Enucleation modalities. The incidences of BNS were pooled using the Cochran-Mantel-Haenszel Method with the random effect model and expressed as Risk Ratios, 95% Confidence Intervals, and p values. Study heterogeneity was assessed utilizing the I(2) value. RESULTS: 72 studies were identified for meta-analysis, 46 comparing TURP vs. Ablation and 26 TURP vs. Enucleation. The pooled incidence of BNS was 1.3% after TURP, 0.66% after enucleation and 1.2% after Ablation. The incidence of BNS was higher after TURP than after Enucleation but the difference was not statistically significant (RR 1.75 95% CI 0.81-3.79, p = 0.16). There was no significant heterogeneity among the studies (I(2) 0%, Chi(2) 4.11, p = 0.90). The incidence of BNS was higher after TURP than after Ablation, but the difference was not statistically significant (RR 1.31, 95% CI 0.82-2.11, p = 0.26) with no significant heterogeneity (I(2) 0%, Chi(2) 21.1, p = 0.51). CONCLUSION: Our study showed no difference in the rate of BNS incidence among randomized trials comparing TURP vs. Ablation vs. Enucleation and can be used as a reference to counsel patients undergoing BPH surgery.

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