首页良性前列腺增生治疗及预后证据详情

A Systematic Review of Reported Ejaculatory Dysfunction in Clinical Trials Evaluating Minimally Invasive Treatment Modalities for BPH

原文:2020年 发布于 Curr Urol Rep 21卷 第12期 54 浏览量:842次 原文链接

作者: Lokeshwar S. D. Valancy D. Lima T. F. N. Blachman-Braun R. Ramasamy R.

作者单位: Department of Urology, Yale Univeristy School of Medicine, 333 Cedar Street, New Haven, CT, 06520-8058, USA. Department of Urology, Miller School of Medicine, University of Miami, 1120 NW 14th Street, 15th Floor, Miami, FL, 33136, USA. Department of Urology, Miller School of Medicine, University of Miami, 1120 NW 14th Street, 15th Floor, Miami, FL, 33136, USA. ramasamy@miami.edu.

归属分类: 良性前列腺增生治疗及预后证据

DOI: 10.1007/s11934-020-01012-y

关键词: Ejaculation/physiology Humans Lower Urinary Tract Symptoms/etiology/physiopathology/therapy Male Minimally Invasive Surgical Procedures Prostatic Hyperplasia/complications/physiopathology/surgery/*therapy Randomized Controlled Trials as Topic Sexual Dysfunction Physiological/etiology Aquablation Benign prostatic hyperplasia Ejaculatory dysfunction Prostate artery embolization Prostatic urethral lift Water vapor thermal therapy

文献简介

PURPOSE OF REVIEW: To explore the sexual outcomes following the novel minimally invasive surgical procedures for benign prostatic hyperplasia- (BPH-) related lower urinary tract symptoms (LUTS), with an emphasis on ejaculatory dysfunction (EjD). RECENT FINDINGS: A database search with a 10-year time restriction was carried out until February 20, 2020 using MEDLINE through the PubMed Platform evaluating minimally invasive treatment modalities for BPH and their effect on EjD. After the article selection, we retrieved data for men randomized in 19 different studies with results in 40 separate published articles investigating minimally invasive BPH surgery and reporting EjD rates. To date, water vapor thermal therapy or Rezūm, prostatic urethral lift (PUL) or UroLift®, prostate artery embolization (PAE), and Aquablation showed acceptable rates (< 2%) of retrograde ejaculation by 1 year and had very low adverse events related to the procedure. Both PUL and Rezūm demonstrated lower rates when compared with PAE and Aquablation. With comparable sexual side effect profiles postoperatively, clinicians may determine which therapeutic modality is optimal for patients based on efficacy and cost-benefit. Further randomized clinical trials are required to directly compare the effect of novel minimally invasive surgical procedures for BPH-related LUTS on ejaculation and sexual function.

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