首页良性前列腺增生治疗及预后证据详情

Systematic review and meta-analysis of prostatic artery embolisation for lower urinary tract symptoms related to benign prostatic hyperplasia

原文:2017年 发布于 Clin Radiol 72卷 第1期 16-22 浏览量:703次 原文链接

作者: Pyo J. S. Cho W. J.

作者单位: Department of Pathology, Eulji University Hospital, Eulji University College of Medicine, Daejeon, Republic of Korea. Department of Urology, Chosun University Hospital, Chosun University School of Medicine, Gwangju, Republic of Korea. Electronic address: uro2097@gmail.com.

归属分类: 良性前列腺增生治疗及预后证据

DOI: 10.1016/j.crad.2016.10.009

关键词: Aged Causality Comorbidity Embolization Therapeutic/*statistics & numerical data Follow-Up Studies Humans Longitudinal Studies Lower Urinary Tract Symptoms/*epidemiology/*prevention & control Male Middle Aged Prostate/blood supply Prostatic Hyperplasia/diagnostic imaging/*epidemiology/*therapy Risk Factors Treatment Outcome

文献简介

AIM: To evaluate the efficacy of prostatic artery embolisation (PAE) in lower urinary tract symptoms (LUTS) related to benign prostatic hyperplasia (BPH) at short- and mid-term follow-up. MATERIALS AND METHODS: The current study included 484 BPH patients from seven eligible studies. A meta-analysis was performed to determine the mean differences in parameters associated with LUTS, including the international prostate symptom score (IPSS), peak urinary flow (Qmax), post-void residual volume (PVR), quality of life score (QoL), prostate-specific antigen level (PSA), and prostatic volume (PV), between baseline and follow-up periods. RESULTS: Nearly all parameters at follow-up of 3-24 months were significantly improved compared to the baseline. Mean differences in IPSS at 3, 6, 12, and 24 months were -14.06 (95% confidence interval [CI]: -16.47 to -11.64), -12.32 (95% CI: -15.57 to -9.08), -16.41 (95% CI: -19.81 to -13.02), and -17 (95% CI: -17.91 to -16.09), respectively. In addition, mean differences of Qmax, PVR, PV, and QoL between the follow-up period and baseline were improved significantly; however, there were no significant differences in PSA at 24 months. CONCLUSION: The present data shows that PAE could improve LUTS by BPH after short- and mid-term follow-up; however, more cumulative studies for long-term follow-up and comparison with other therapeutic modalities will be needed.

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