首页良性前列腺增生治疗及预后证据详情

A Systematic Review of Prostatic Artery Embolization in the Treatment of Symptomatic Benign Prostatic Hyperplasia

原文:2017年 发布于 Cardiovasc Intervent Radiol 40卷 第5期 655-663 浏览量:1457次 原文链接

作者: Kuang M. Vu A. Athreya S.

作者单位: Michael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada. St. Joseph's Healthcare, Hamilton, ON, Canada. sathreya@stjoes.ca. McMaster University Faculty of Health Sciences, Centre for Interventional Radiology and Oncology, Josephs Healthcare Hamilton, Rm. T0112, 50 Charlton Ave. E., Hamilton, ON, L8N 4A6, Canada. sathreya@stjoes.ca.

归属分类: 良性前列腺增生治疗及预后证据

DOI: 10.1007/s00270-016-1539-3

关键词: Aged Embolization Therapeutic Humans Lower Urinary Tract Symptoms/complications/therapy Male Prostate/blood supply/diagnostic imaging Prostatic Hyperplasia/complications/*therapy Treatment Outcome Bph Prostate artery embolisation Quality of life

文献简介

PURPOSE: To summarize current evidence on outcomes and complications of prostatic artery embolization as a treatment for patients with lower urinary tract symptoms secondary to benign prostatic hyperplasia. METHODS AND MATERIALS: A database search of MEDLINE, Embase, Web of Science, and Cochrane Library was performed for published literature up to August 2015 concerning PAE in the treatment of BPH. Inclusion and exclusion criteria were applied by two independent reviewers, and disagreements were resolved by consensus. Peer-reviewed studies concerning PAE with BPH with a sample size >10 and at least one measured parameter were included. RESULTS: The search yielded 193 articles, of which ten studies representing 788 patients, with a mean age of 66.97 years, were included. Patients had LUTS ranging from moderate to severe. At 6 months following procedure, PV, PVR, Qmax, IPSS, and QoL were significantly improved (P < 0.05), while for PSA there was no significant change. At 12 and 24 months, PV, PSA, PVR, Qmax, IPSS, and QoL were significantly improved (P < 0.05). IIEF was unchanged at 6 and 12 months but was significantly reduced at 24 months. CONCLUSION: This suggests that PAE is effective in treating LUTS in the short and intermediate term.

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