首页良性前列腺增生治疗及预后证据详情

Diagnostic value of urodynamic bladder outlet obstruction to select patients for transurethral surgery of the prostate: Systematic review and meta-analysis

原文:2017年 发布于 PLoS One 12卷 第2期 e0172590 浏览量:885次 原文链接

作者: Kim M. Jeong C. W. Oh S. J.

作者单位: Department of Urology, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Republic of Korea. Department of Urology, Seoul National University College of Medicine, Seoul National University Hospital, Seoul, Republic of Korea.

归属分类: 良性前列腺增生治疗及预后证据

DOI: 10.1371/journal.pone.0172590

关键词: Aged Humans Male Middle Aged *Patient Selection Prostate/surgery Prostatic Hyperplasia Quality of Life *Transurethral Resection of Prostate Treatment Outcome Urinary Bladder Neck Obstruction *Urodynamics

文献简介

PURPOSE: To investigate the diagnostic value of urodynamic bladder outlet obstruction (BOO) in the selection of patients for transurethral surgery of the prostate. MATERIALS AND METHODS: We systematically searched online PubMed, Embase, and Cochrane Library databases from January 1989 to June 2014. RESULTS: A total of 19 articles met the eligibility criteria for this systematic review. The eligible studies included a total of 2321 patients with a median number of 92 patients per study (range: 12-437). Of the 19 studies, 15 conducted conventional transurethral prostatectomy (TURP), and 7 used other or multiple modalities. In urodynamic bladder outlet obstruction (BOO) positive patients, the pooled mean difference (MD) was significant for better improvement of the International Prostate Symptom Score (IPSS) (pooled MD, 3.48; 95% confidence interval [CI], 1.72-5.24; p < 0.01; studies, 16; participants, 1726), quality of life score (QoL) (pooled MD, 0.56; 95% CI, 0.14-1.02; p = 0.010; studies, 9; participants, 1052), maximal flow rate (Qmax) (pooled MD, 3.86; 95% CI, 2.17-5.54; p < 0.01; studies, 17; participants, 1852), and post-void residual volume (PVR) (pooled MD, 32.46; 95% CI, 23.34-41.58; p < 0.01; studies, 10; participants, 1219) compared with that in non-BOO patients. Some comparisons showed between-study heterogeneity despite the strict selection criteria of the included studies. However, there was no clear evidence of publication bias in this meta-analysis. CONCLUSIONS: Our meta-analysis results showed a significant association between urodynamic BOO and better improvements in all treatment outcome parameters. Preoperative UDS may add insight into postoperative outcomes after surgical treatment of benign prostatic hyperplasia.

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