首页良性前列腺增生治疗及预后证据详情

Short- to Midterm Safety and Efficacy of Prostatic Artery Embolization: A Systematic Review

原文:2016年 发布于 J Vasc Interv Radiol 27卷 第10期 1487-1493.e1 浏览量:808次 原文链接

作者: Cizman Z. Isaacson A. Burke C.

作者单位: Department of Radiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina. Electronic address: ziga.cizman@gmail.com. Department of Radiology, University of North Carolina School of Medicine, Chapel Hill, North Carolina.

归属分类: 良性前列腺增生治疗及预后证据

DOI: 10.1016/j.jvir.2016.04.015

关键词: *Arteries Embolization Therapeutic Humans Lower Urinary Tract Symptoms/etiology Male Prostate/*blood supply Prostatic Hyperplasia/complications/diagnosis/*therapy Quality of Life Risk Factors Time Factors Treatment Outcome

文献简介

PURPOSE: To review the available safety and efficacy data for prostatic artery embolization (PAE) in the treatment of benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: PubMed was searched for publications that included PAE for the treatment of BPH through May 2015. Two independent reviewers determined the appropriateness for inclusion of each article and compiled data by using pooled weighted means and standard deviations. RESULTS: The literature search identified 161 articles, of which 7 studies, with a total of 562 patients, met all inclusion/exclusion criteria. PAEs were performed bilaterally in 85% of patients, unilaterally in 12%, and unsuccessfully in 3%. International Prostate Symptom Score decreased from 24.51 ± 6.12 at baseline to 10.42 ± 5.39 at 6 months. Quality of life score decreased from 4.76 ± 0.98 at baseline to 2.51 ± 1.13 at 6 months. Peak urinary flow rate increased from 8.41 mL/s ± 2.63 at baseline to 15.44 mL/s ± 5.64 at 6 months. Postvoid residual measurement decreased from 105.94 mL ± 76.77 at baseline to 39.57 mL ± 15 at 6 months. Prostate-specific antigen level decreased from 4.79 ng/mL ± 5.42 at baseline to 3.16 ng/mL ± 1.5 at 6 months. None of these parameters showed clinically significant changes from 6 months to 12 months. Total prostate volume decreased from 96.56 cm3 ± 35.47 at baseline to 46.73 cm3 ± 20.51 at 12 months. There were 200 minor complications and 1 major complication. CONCLUSIONS: PAE improves lower urinary tract symptoms caused by BPH, with a favorable short- to midterm safety profile.

热门文献