We aimed to provide guidelines for the evidence-based diagnosis and treatment of benign prostatic hyperplasia (BPH) and basic information about diagnostic testing, drug therapy, and surgical treatment. The target population in which to apply the guideline is men over 40 years of age who complain of lower urinary tract symptoms (LUTS). The intended users of this guideline are all physicians who care for men with BPH. This comprehensive guideline covers the diagnosis and treatment of BPH with key questions that can be applied in clinical practice.