首页膀胱肿瘤病因/危险因素证据详情

尿液中 LncRNA UCA1 检测对膀胱癌诊断价值的 Meta 分析

原文: 2017 年 发布于 Aktuelle Urologie 浏览量:206次 原文链接

作者: 孔令启 屈艳琳

作者单位: Department of Urology, Institute of Urology, West China Hospital, Sichuan University, Chengdu, China. West China School of Clinical Medicine, Sichuan University, Chengdu, China.

归属分类: 膀胱肿瘤病因/危险因素证据

DOI: 10.1007/s00345-022-04188-9

文献简介

BACKGROUND: Enhanced recovery pathways, also known as fast-track protocols, have been adopted since the early 2000s by various surgical specialties with the goal of improving patient outcomes and reducing the cost burden of major surgery on the health care system. OBJECTIVE: To review the scientific literature on the origin of enhanced recovery pathways, track the contemporary utilization of such practices for patients undergoing radical cystectomy, and analyze the available data regarding their effect on morbidity, mortality, and treatment cost. METHODS: A literature search of multiple electronic databases was undertaken. Manuscripts including patients undergoing radical cystectomy were chosen based on predefined criteria with an emphasis on randomized controlled trials and cohort studies. Strength of evidence for each study that met inclusion criteria was assessed based on the risk of bias, consistency, directness, and precision. RESULTS: Database searches resulted in 1,236 potentially relevant articles. A total of 485 articles were selected for full-text dual review and 106 studies in 52 publications met the inclusion criteria. CONCLUSION: The utilization of enhanced recovery pathways with the goal of improving overall patient morbidity and mortality is well supported in the literature, however standardization of implementation and adherence across institutions is lacking, and their direct efficacy on reducing preventable treatment related expenditures is unconfirmed.

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