首页膀胱肿瘤治疗及预后证据详情

Comparison of the prognosis of primary and progressive muscle-invasive bladder cancer after radical cystectomy: A systematic review and meta-analysis

原文: 2018 年 发布于 Oncotarget 浏览量:393次

作者: Chen J. R. Zhang H. R. Sun G. X. Zhang X. M. Zhao J. E. Liu J. D. Shen P. F. Shi M. Zeng H.

作者单位: Department of Urology, Tianjin Medical University General Hospital, Tianjin, 300052, China. Electronic address: songyuxuan@tmu.edu.cn. Department of Urology, Linzi District People's Hospital, Zibo 255400, China. Electronic address: qixiangjie1@163.com. Department of Urology, Tianjin Medical University General Hospital, Tianjin, 300052, China. Electronic address: liutjykdx@163.com.

归属分类: 膀胱肿瘤治疗及预后证据

DOI: 10.1111/bju.15276

文献简介

Background and Objective: Controversial results of the association between tea (black tea, green tea, mate, and oolong tea) consumption and risk of bladder cancer were reported among epidemiological studies. Thus, we performed a meta-analysis of observational studies to investigate the association. Methods: We searched the PubMed and Embase for studies of tea consumption and bladder cancer that were published in any language up to March, 2016. Cohort or case-control studies were included in the meta-analysis. All statistical analyses were performed in Stata 12.0 software. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to assess the relationship between tea consumption and risk of bladder cancer. Results: Totally, 25 case-control studies (15 643 cases and 30 795 controls) and seven prospective cohort studies (1807 cases and 443 076 participants) were included. The meta-analysis showed that tea consumption was not significantly associated with bladder cancer risk (OR = 0.96, 95% CI 0.861.06) (in a comparison of highest vs. lowest category). No non-linearity association was observed between tea consumption and bladder cancer risk (P = 0.51 for non-linearity). Specific analysis for black tea, green tea, and mate yielded similar results. The dose-response analysis showed the summary OR for an increment of 1 cup/day of tea consumption was 1.01 (95% CI 0.971.05). Conclusion: Results based on current meta-analysis indicated that no significant association was observed between tea consumption and risk of bladder cancer.