首页膀胱肿瘤病因/危险因素证据详情

Incidence and risk factors of suicide among patients diagnosed with bladder cancer: A systematic review and meta-analysis

原文: 2021 年 发布于 Eur Urol Oncol 17 卷 第 1-2 期 Cd011935 浏览量:157次

作者: Guo Z. Gu C. Li S. Gan S. Li Y. Xiang S. Gong L. Wang S.

作者单位: Department of Urology, Comprehensive Cancer Center, Vienna General Hospital, Medical University of Vienna, Vienna, Austria. Men's Health and Reproductive Health Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Department of Urology, Medical University of Silesia, Zabrze, Poland. Department of Urology, The Jikei University School of Medicine, Tokyo, Japan. Institute for Urology and Reproductive Health, Sechenov University, Moscow, Russia. Department of Urology, King Faisal Medical City, Abha, Saudi Arabia. Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan. Department of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Department of Urology, University Hospital Zurich, Zurich, Switzerland. Research Center for Evidence Based Medicine, Tabriz University of Medical Sciences, Tabriz, Iran. Department of Urology, King Fahad Specialist Hospital, Dammam, Saudi Arabia. Cancer Prognostics and Health Outcomes Unit, University of Montreal Health Center, Montreal, Canada. Department of Urology, Motol University Hospital, 2nd Faculty of Medicine, Charles University Praha, Prague, Czech Republic. Department of Urology, Weill Cornell Medical College, New York, New York, USA. Department of Urology, University of Texas Southwestern, Dallas, Texas, USA. Department of Urology, Second Faculty of Medicine, Charles University, Prague, Czech Republic. Karl Landsteiner Institute of Urology and Andrology, Vienna, Austria.

归属分类: 膀胱肿瘤病因/危险因素证据

DOI: 10.1080/14737140.2022.2147511

关键词: Humans Muscle Skeletal/*pathology Neoplasm Invasiveness ROC Curve Radiography/*methods Research Design Urinary Bladder Neoplasms/*diagnosis Bladder cancer Diagnostic imaging Magnetic resonance imaging

文献简介

Background: To minimize toxicity due to radiotherapy in patients with prostate cancer, high bladder volume reproducibility is essential. Water consumption is often used to increase bladder volume reproducibility, but the optimal amount of water required to be consumed remains unclear. We aimed to analyzed the relationship between water consumption and bladder volume reproducibility in patients undergoing radiotherapy for prostate cancer. Methods: We conducted a systematic review and meta-analysis of randomized controlled trials and cohort studies that assessed bladder volume change after water consumption in patients with prostate cancer undergoing radiotherapy. MEDLINE, Embase, and Cochrane Central Register of Controlled Trials were searched for relevant studies published from database inception up until July 4, 2020. The NewcastleeOttawa Scale was used to evaluate the risk of bias in the included studies. The outcome was the mean difference (MD) of bladder volume after water consumption, evaluated through meta-analysis using a random-effects model. Results: Ten cohort studies and one randomized controlled trial with a total of 417 patients were included. For 300-400 ml water consumption, the bladder volume MD between during treatment and at computer tomography-simulation (95% confidence interval [CI]) was -11.97 (-51.68 to 27.74), was -45.99 (-82.85 to -9.13) for 500-540 ml water consumption and -45.92 (-78.86 to -12.98) for water consumption until full-bladder sensation was reached. Conclusion: Consuming 300-400 ml of water potentially leads to the best bladder volume reproducibility; moreover, the higher the water consumption volume, the lower the bladder volume reproducibility.

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