首页膀胱肿瘤病因/危险因素证据详情

Microbiome in Bladder Cancer: A Systematic Review

原文: 2022 年 发布于 Computational and Mathematical Methods in Medicine 40 卷 第 06 期 336-344 浏览量:208次

作者: Gwon Y. N. Park J. J. Lee K. S. Lee K. H. Kim T. H. Kim J. H.

作者单位: Department of Urology, Medical University of Vienna, Vienna, Austria. Careggi Hospital, University of Florence, Florence, Italy. Kantonsspital Winterthur, Winterthur, Switzerland. Department of Special Surgery, Jordan University Hospital, University of Jordan, Amman, Jordan. Department of Cell and Molecular Biology, University of Medicine and Pharmacy, Tirgu Mures, Romania. Division of Urology, University of Montreal Health Center, Montreal, Quebec, Canada. Departments of Urology, Jikei University School of Medicine, Tokyo, Japan. Karl Landsteiner Institute of Urology and Andrology, Vienna, Austria. Weill Cornell Medical College, New York, New York. University of Texas Southwestern Medical Center, Dallas, Texas.

归属分类: 膀胱肿瘤病因/危险因素证据

DOI: 10.1016/j.envpol.2020.115328

关键词: 膀胱肿瘤 根治性膀胱切除术 机器人 剖腹术 Meta分析

文献简介

CONTEXT: Improving efficiency of follow-up for non-muscle invasive bladder tumours (NMIBC) without risking disease progression through delays of recurrence diagnosis, is a highly relevant field of research. OBJECTIVE: The aim of our systematic review was to investigate whether the available evidence support alternative follow-up cytoscopic schedules with respect to oncological safety, compared to those currently given in clinical guidelines for NMIBC. Evidence acquisition we included prospective studies investigating cystoscopy based follow-up schedules including, but not restricted to, comparison of two or more different follow-up schedules with respect to oncological safety measured by recurrence free survival, progression free survival, and overall survival. We allowed for supplementation of modalities such as urinary biomarkers. We screened 680 studies identified by a systematic literature search and, based on our inclusion and exclusion criteria, we included three studies for the narrative synthesis of evidence. CONCLUSION: In our systematic search of the literature, we found only low level evidence to support current or alternative cystoscopic follow-up schedules. Clinical trials directly aimed at investigating novel follow-up schedules for NMIBC are needed before substantial changes to existing clinical guidelines can be made.

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