首页膀胱肿瘤诊断证据详情

Utility of Artificial Intelligence in the Cystoscopic Detection of Bladder Cancer: A Systematic Review and Meta-Analysis

原文: 2021 年 发布于 Cancers (Basel) 146 卷 第 47 期 650-662 浏览量:228次

作者: Ganesananthan S. Ganesananthan S. Simpson B. S. Norris J. M.

作者单位: Department of Urology, National Taiwan University Hospital, College of Medicine National Taiwan University, Taipei, Taiwan Department of Urology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan. Department of Urology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan Department of Urology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. Department of Urology, Chi Mei Medical Center, Tainan, Taiwan. Department of Urology, Ditmanson Medical Foundation Chiayi Christian Hospital, Chiayi, Taiwan. Department of Urology, Shuang Ho Hospital, Taipei Medical University, New Taipei City, Taiwan Department of Urology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan TMU Research Center of Urology and Kidney, Taipei Medical University, Taipei, Taiwan. Electronic address: 08253@s.tmu.edu.tw. Graduate Institute of Clinical Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan Department of Medical Research, Shuang Ho Hospital, Taipei Medical University, New Taipei, Taiwan. Electronic address: d508091002@tmu.edu.tw.

归属分类: 膀胱肿瘤诊断证据

DOI: 10.3389/fonc.2021.614041

关键词: Aged Catheterization Female Hospitalization Humans Lasers Solid-State/*therapeutic use Male Middle Aged Muscles/*pathology Neoplasm Recurrence Local/pathology Postoperative Complications/etiology Publication Bias Treatment Outcome Urethral Stricture/surgery Urinary Bladder Neoplasms/pathology/*surgery *Urologic Surgical Procedures Holmium laser Meta-analysis Non-muscle-invasive bladder cancer Transurethral resection

文献简介

Objective: Intravesical Bacillus Calmette-Guerin (BCG) is an effective treatment in non-muscle-invasive bladder cancer, however, extravesical BCG infection may occur in remote organs as a potentially serious complication. Researchers aimed to assess whether a different timing of BCG infection after intravesical administration of BCG could be identified and estimated for each single involved organ. Methods: We performed a systematic literature review over systemic and genitourinary BCG infection case reports, including 271 published case reports for a total of 307 patients. Demographic data, clinical features, and timing of BCG infection development were collected and analyzed for each patient. Results: BCG infection developed with a different timing from last instillation, depending on the involved organ. Among the genitourinary complications, penile lesions occurred as early as 1 (1;3) weeks, while orchiepididymitis occurred as late as 56 (6.25;156) weeks. At the same time, granulomatous hepatitis and lungs involvement such as miliary pulmonary BCG infection occurred earlier, with a median time of 1 (1;4) and 1 (1;6) weeks respectively, whereas vascular, osteoarticular, and muscular complications developed with a median timing from last instillation of 52 (20;104), 68 (14;156), and 93 (29;156) weeks, respectively. The analysis detected a cluster between lungs, liver, and bone marrow complications on one side and muscular and osteoarticular or vascular complications on the other side was also observed. Conclusions: BCG infection after intravesical BCG for bladder cancer may develop even several months or years after the last instillation, depending on the involved organs. When BCG infection interests one or more organ, 2 main associative patterns are common: one involving lungs, liver, and bone marrow, with earlier occurrence but lower rates of microbiological diagnosis achievement, and one involving muscular and osteoarticular or vascular districts, with later occurrence but higher rates of microbiological evidence. (C) 2020 Elsevier Inc. All rights reserved.

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