The Importance of Hospital and Surgeon Volume as Major Determinants of Morbidity and Mortality After Radical Cystectomy for Bladder Cancer: A Systematic Review and Recommendations by the European Association of Urology Muscle-invasive and Metastatic Bladder Cancer Guideline Panel

原文： 2020 年发布于 World J Urol 12 卷第 8 期 34-40  浏览量：240次

作者： Bruins H. M. Veskimae E. Hernandez V. Neuzillet Y. Cathomas R. Comperat E. M. Cowan N. C. Gakis G. Espinos E. L. Lorch A. Ribal M. J. Rouanne M. Thalmann G. N. Yuan Y. H. van der Heijden A. G. Witjes J. A.

作者单位： Division of Surgery and Interventional Science, University College London, 3rd Floor Charles Bell House, 43-45 Foley Street, London W1W 7TS, UK Department of Urology, University College London Hospital at Westmoreland Street, 16-18 Westmoreland Street, London W1G 8PH, UK. Electronic address: wei.tan@ucl.ac.uk. Department of Urology, Rush University Medical Center, 1653 W Congress Pkwy, Chicago, IL 60612, USA. School of Public Health, London School of Hygiene & Tropical Medicine, Keppel Street, London WC1E 7HT, UK. Division of Surgery and Interventional Science, University College London, 3rd Floor Charles Bell House, 43-45 Foley Street, London W1W 7TS, UK Department of Urology, University College London Hospital at Westmoreland Street, 16-18 Westmoreland Street, London W1G 8PH, UK. UCL Cancer Institute, University College London, Paul O'Gorman Building, 72 Huntley Street, London WC1E 6DD, UK. Division of Surgery and Interventional Science, University College London, 3rd Floor Charles Bell House, 43-45 Foley Street, London W1W 7TS, UK.

归属分类：膀胱肿瘤治疗及预后证据

DOI： 10.23736/s0393-2249.20.03680-2

关键词： Adult Aged Air Pollution/*adverse effects Carcinogens Environmental/*adverse effects Cohort Studies Environmental Exposure/*adverse effects Europe/epidemiology Female Humans Incidence Male Meta-Analysis as Topic Middle Aged Nitrogen Oxides/adverse effects Particulate Matter/adverse effects Prospective Studies Risk Factors Urinary Bladder Neoplasms/*epidemiology/etiology Air pollution Bladder cancer Environment Prevention

Background: Bladder cancer is the fourth most common malignancy in men and a considerable disease burden globally. Multiple studies have focused on the accuracy of optical coherence tomography for bladder cancer diagnosis; however, the findings are inconsistent. Here, we assessed the accuracy of optical coherence tomography for bladder cancer diagnosis. Methods: Embase, PubMed, Medline, Web of Science, and the Cochrane Library database were searched for relevant studies from the earliest date available through March 11, 2019. Studies evaluating the accuracy of optical coherence tomography bladder cancer diagnosis were included. Pooled sensitivity, specificity, and area under the curve values of weighted symmetric summary receiver operating curves, were calculated at the perlesion level. Results: Eleven studies, with a total of 1933 lesions, were included in the final analysis. The pooled results indicated that optical coherence tomography can differentiate bladder cancer from benign lesions: sensitivity, 94.9% (95% confidence interval: 92.7%-96.6%); specificity, 84.6% (95% confidence interval: 82.6%-86.4%); area under the curve, 0.97. Moreover, compared with optical coherence tomography alone, combined optical coherence tomography and fluorescence cystoscopy increased the diagnostic accuracy (sensitivity, 94.3% vs. 87.3%; specificity, 89.2% vs. 73.9%). Cross-polarization optical coherence tomography could also distinguish bladder cancer from normal tissue: sensitivity, 92.0% (95% confidence interval: 87.0%-95.6%); specificity, 84.4% (95% confidence interval: 81.7%-86.9%); area under the curve, 0.95. Conclusions: Optical coherence tomography can accurately differentiate malignant from benign bladder lesions, particularly when combined with fluorescence cystoscopy.