首页膀胱肿瘤治疗及预后证据详情

Predicting Recurrence and Progression in Patients with Non-Muscle-Invasive Bladder Cancer: Systematic Review on the Performance of Risk Stratification Models

原文: 2022 年 发布于 Abdom Radiol (NY) 14 卷 第 10 期 573-577 浏览量:141次

作者: Guerrero-Ramos F. Subiela J. D. Rodriguez-Faba O. Aumatell J. Manfredi C. Bozzini G. Romero-Otero J. Counago F.

作者单位: Department of Urology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea. urosyc@cau.ac.kr. Department of Urology, Hyundae General Hospital, Chung-Ang University College of Medicine, Namyangju, Korea. Department of Urology, Hanil General Hospital, Seoul, Korea. Department of Urology, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea.

归属分类: 膀胱肿瘤治疗及预后证据

DOI: 10.1016/j.critrevonc.2021.103570

关键词: 非肌层浸润性膀胱癌 表柔比星 膀胱内化疗 复发 进展

文献简介

Objective. To systematically evaluate the impact of diabetes on the prognosis of bladder cancer patients after radical cystectomy (RC). Methods. PubMed, Embase, and Cochrane Library databases were selected from inception to October 2021. The studies on the effects of diabetes on bladder cancer patients after RC were included for analysis. The inclusion and exclusion criteria were independently selected for literature screening, the quality of the included studies was evaluated, and data were extracted. Results. A total of 5 cohort studies were included, with a total of 2 661 subjects, including 391 cases in the diabetic group, non-diabetes. Meta-analysis results show that diabetes increases the overall risk of death in patients after RC (HR = 1.36, 95% CI: 1.30 similar to 1.43, P < 0.001) and the risk of tumor-specific death (HR = 1.59, 95% CI: 1.29 similar to 1.95, P < 0.001). Sensitivity analysis shows that the stability of this study is well. Conclusion. Diabetes was an independent risk factor in terms of overall and cancer-specific survival in patients who underwent RC.

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