首页膀胱肿瘤治疗及预后证据详情

The efficacy and safety of thulium laser resection of bladder tumor versus standard transurethral resection in patients with non-muscle-invasive bladder cancer: a systematic review and meta-analysis

原文: 2021 年 发布于 临床泌尿外科杂志 112 卷 第 1 期 795-804 浏览量:223次

作者: Chai Y. M. Cui Y. S. Zhang X. Y. Zong H. T. Zhou Z. B. Zhang Y.

作者单位: aDivision of Epidemiology, Department of Health Informatics and Public Health, Tohoku University School of Public Health, Graduate School of Medicine, Sendai bDepartment of Epidemiology and Public Health, Kanazawa Medical University, Uchinada cDivision of Cancer Epidemiology and Prevention, Miyagi Cancer Center Research Institute, Natori dDepartment of Public Health, Yamagata University Graduate School of Medicine, Yamagata, Japan.

归属分类: 膀胱肿瘤治疗及预后证据

DOI: 10.23736/s0393-2249.19.03376-9

关键词: *Cystectomy/methods Humans Postoperative Complications/*epidemiology Prognosis Survival Rate Urinary Bladder Neoplasms/*mortality/*surgery Bladder cancer clinical markers morbidity mortality radical cystectomy survival

文献简介

Objective: Epidemiologic studies investigating the association between dietary carbohydrates as well as glycemic index and glycemic load (markers of carbohydrate quality) and bladder cancer risk have yielded inconsistent results. The aim of the present meta-analysis is to summarize the evidence on this association. Materials and Methods: A comprehensive literature search of articles published by December 2019 was performed in PubMed, Scopus, and Web of Science databases. A random-effects model was used to calculate the pooled odds ratios (ORs) and their corresponding 95% confidence intervals (CIs). Results: Twelve observational studies were included in the final analysis. There was no evidence of an association between consumption of carbohydrates and bladder cancer risk (pooled OR, 1.04; 95% CI, 0.92-1.17). No statistically significant association between glycemic load and bladder cancer was likewise found (pooled OR, 1.10; 95% CI, 0.85-1.42). However, there was a significant positive association between glycemic index and bladder cancer risk (pooled OR, 1.25; 95% CI, 1.11-1.41). In the dose-response analysis, the pooled OR (95% CI) per 10 units of glycemic index per day was 1.02 (95% CI, 1.01-1.04). Conclusion: In this meta-analysis, glycemic index showed a positive linear association with bladder cancer risk.

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