首页膀胱肿瘤治疗及预后证据详情

腹腔镜膀胱癌根治性切除术体内与体外回肠膀胱术疗效的 Meta 分析

原文: 2019 年 发布于 Eur Urol Oncol 719 卷 第 6 期 1260-1265 浏览量:205次 原文链接

作者: 张勇 朱猛

作者单位: Department of Urology, Northern Ontario School of Medicine, Thunder Bay, Ontario. vahidmehrnoush7@gmail.com. Inflammation Research Network-Snyder Institute for Chronic Disease, Departments of Physiology and Pharmacology and Medicine, University of Calgary Cumming School of Medicine, Calgary, Alberta. stacy.ggibson@gmail.com. Department of Urology, Northern Ontario School of Medicine, Thunder Bay, Ontario. drahmedfali@gmail.com. Department of Urology, Southern Alberta Institute of Urology, Calgary, Alberta. erichyndman@shaw.ca.

归属分类: 膀胱肿瘤治疗及预后证据

DOI: 10.1155/2022/6575605

关键词: Humans Neoplasm Recurrence Local/*diagnosis Obesity/complications/*diagnosis Risk Factors Urinary Bladder Neoplasms/*diagnosis Bladder cancer Obesity Recurrence Survival

文献简介

The association between dietary fat intake and bladder cancer had been inconsistent in the previous epidemiological studies. The aim of this study was to investigate the difference between fat intake and bladder cancer risk. Databases of PubMed, Embase, and Web of Science were systematically searched for suitable studies from inception to June 2018. A meta-analysis was performed to analyze the efficacy of dietary fat intake on bladder cancer risk. A Forest plot was prepared to indicate the relationship. Ten citations were used in this study. The Funnel plot suggested highest category of dietary fat intake could increase the risk of bladder cancer (summarized relative risk (RR)=1.279, 95% confidence interval (CI)=1.036-1.577, I-2=53.2%, P (for heterogeneity) = 0.019). A positive association was found among European populations (summarized RR=1.359, 95% CI=1.027-1.798), but not in North American populations. The association was not significant in the subgroup analysis by fat type on bladder cancer risk. Egger test (P=0.239) and Funnel plot showed there was no significant publication bias in the included publications. In conclusions, compared with the lowest category of dietary fat intake, the highest category could significantly increase the bladder cancer risk, especially among European populations. As some limitations existed in our analysis, large scale studies with detailed amount of dietary fat intake are needed to verify our results.

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