Anticoagulants Blood Transfusion *Deprescriptions Dysuria/epidemiology Humans Laser Therapy Male Operative Time Postoperative Complications/epidemiology Prostatic Hyperplasia Reoperation Transurethral Resection of Prostate Urethral Stricture/epidemiology Urinary Tract Infections/epidemiology Anticoagulant Benign prostate hyperplasia (BPH) Lower urinary tract symptom (LUTS) Photoselective vaporization (PVP)

Administration Oral Fibrinolytic Agents/*administration & dosage Humans Lasers Solid-State Male Prostatic Hyperplasia Risk Factors Antithrombotic Benign prostate hyperplasia (BPH) Holmium laser enucleation of the prostate (HoLEP) Perioperative safety

Aged Catheterization Humans *Laser Therapy Lower Urinary Tract Symptoms/physiopathology Male Prostate/physiopathology Prostatic Hyperplasia/physiopathology Randomized Controlled Trials as Topic *Transurethral Resection of Prostate Treatment Outcome benign prostatic hyperplasia (BPH) button-type bipolar plasma vaporization (BTPV) lower urinary tract symptoms (LUTS) transurethral resection (TURP)

*Bipolar Disorder China Humans Male Prostatectomy *Prostatic Hyperplasia Quality of Life *Transurethral Resection of Prostate Treatment Outcome Benign prostatic hyperplasia High-risk and senior patients Meta-analysis Systematic review Transurethral bipolar plasmakinetic prostatectomy

Enucleation Resection of prostate Benign prostatic hyperplasia Meta-analysis

Phosphodiesterase type 5 inhibitor Lower urinary tract symptoms Benign prostatic hyperplasia Meta-analysis

Statins Benign prostatic hyperplasia Lower urinary tract symptoms Meta-analysis

Aged Holmium Humans *Laser Therapy Lasers Solid-State Male Postoperative Complications/etiology Prostate/*radiation effects Prostatic Hyperplasia Publication Bias Randomized Controlled Trials as Topic Thulium Treatment Outcome Efficacy Enucleation Holmium laser Meta-analysis Safety Thulium laser

Benign prostate hyperplasia metabolic syndrome meta-analysis

Humans Lower Urinary Tract Symptoms Male Postoperative Complications/*etiology Prostatic Hyperplasia Randomized Controlled Trials as Topic Sexual Dysfunction Physiological/*etiology Urologic Surgical Procedures Male/*adverse effects

Humans Laparoscopy/*statistics & numerical data Male Margins of Excision Operative Time Prostate/surgery Prostate-Specific Antigen/blood Prostatectomy/*statistics & numerical data Prostatic Hyperplasia Prostatic Neoplasms/blood Robotic Surgical Procedures/*statistics & numerical data Treatment Outcome Urinary Bladder *laparoscopy *prostatectomy *prostatic neoplasms *robotic surgical procedures *urinary bladder neck obstruction

Female Humans Lower Urinary Tract Symptoms/*drug therapy Male Prostatic Hyperplasia/complications/*drug therapy Randomized Controlled Trials as Topic Sexual Dysfunction Physiological Treatment Outcome

Benign prostatic hyperplasia chronic kidney disease systematic review meta-analysis

Prostate artery embolisationl benign prostatic hyperplasia systematic review meta-analysis

Adrenergic alpha-1 Receptor Antagonists/*administration & dosage Adrenergic beta-3 Receptor Agonists/administration & dosage Cholinergic Antagonists/administration & dosage Drug Therapy Combination Humans Lower Urinary Tract Symptoms/*drug therapy Male Phosphodiesterase 5 Inhibitors/*administration & dosage Prostatic Hyperplasia/complications Quality of Life Randomized Controlled Trials as Topic 5-alpha reductase inhibitor Lower urinary tract symptoms alpha blockers anticholinergic: systematic review benign prostatic hyperplasia randomized trials

Capsules Drugs Chinese Herbal Humans Male Prostatic Hyperplasia/*drug therapy Randomized Controlled Trials as Topic Treatment Outcome Urinary Retention benign prostatic hyperplasia meta-analysis randomized controlled trial systematic review Qianlieshutong Capsules

Blood Transfusion Clinical Trials as Topic Humans Length of Stay Male Minimally Invasive Surgical Procedures Operative Time Prostate Prostatectomy Prostatic Hyperplasia Quality of Life Treatment Outcome Urinary Retention *benign prostatic hyperplasia *laparoscopic *minimally invasive simple prostatectomy *open simple prostatectomy *robotic

Photoselective green light laser vaporisation traditional transurethral resection benign prostate hyperplasia meta-analysis

Aged Humans Lower Urinary Tract Symptoms/*etiology Male Prostatic Hyperplasia Transurethral Resection of Prostate Urethra/physiopathology

Embolization Therapeutic Humans Male Prostate/*blood supply/pathology Prostatic Hyperplasia/diagnosis/*therapy Transurethral Resection of Prostate Treatment Outcome Benign prostatic hyperplasia Meta-analysis Prostatic artery embolization Transurethral resection of the prostate PUBLICATION: Not applicable. COMPETING INTERESTS: The authors declare that they have no competing interests. PUBLISHER’S NOTE: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.