Cystectomy France Humans Lymphatic Irradiation Palliative Care Patient Positioning Radiation Oncology Radiotherapy Dosage Radiotherapy Adjuvant Radiotherapy Conformal Urinary Bladder Neoplasms/diagnostic imaging/pathology/*radiotherapy/surgery Bladder cancer Cancers de la vessie Chemoradiation Chimioradiothérapie French society for radiation oncology Guidelines Radiation therapy Radiothérapie Recommandations Société française de radiothérapie oncologique

*BCG Vaccine/adverse effects Female Humans Male Randomized Controlled Trials as Topic *Urinary Bladder Neoplasms/drug therapy Administration intravesical Adverse effects Recurrence Urinary bladder neoplasms

Radical cystectomy bladder preservation distant metastasis rate (DMR) muscular invasive bladder cancer (MIBC) survival rate form (available at https://dx.doi.org/10.21037/tau-21-564). The authors have no conflicts of interest to declare.

Follow-Up Studies Humans Medical Oncology Practice Guidelines as Topic *Urinary Bladder Neoplasms/diagnosis/therapy

Humans *Urinary Bladder Neoplasms/diagnosis/therapy/pathology BCG Vaccine/therapeutic use Cystectomy Administration Intravesical Urinary Bladder/pathology Bcg Bladder Bladder tumours Cancer Carcinome urothélial Cystectomie Cytologie urinaire Survie Survival Tumeurs de la vessie Urine cytology Urothelial carcinoma Vessie

Humans *Cystectomy/methods *Urinary Bladder Neoplasms/radiotherapy/surgery Urinary Bladder Radiotherapy Adjuvant/methods Prospective Studies Margins of Excision

Aged Cystectomy/adverse effects Humans Quality of Life Ureterostomy *Urinary Bladder Neoplasms/surgery *Urinary Diversion/adverse effects Cystectomy Systematic Review [Publication Type] Urinary Bladder Neoplasms

Antineoplastic Combined Chemotherapy Protocols/adverse effects Bayes Theorem *Carcinoma Transitional Cell/drug therapy/surgery Humans Network Meta-Analysis *Urinary Bladder Neoplasms/drug therapy/surgery Ici Pd-1 Pd-l1 adjuvant therapy chemotherapy urothelial carcinoma

Adjuvants Immunologic/therapeutic use Administration Intravesical Aged BCG Vaccine/therapeutic use Humans *Mycobacterium bovis Neoplasm Invasiveness Neoplasm Recurrence Local *Urinary Bladder Neoplasms

Blood Loss Surgical/statistics & numerical data Blood Transfusion/statistics & numerical data Cystectomy/*methods Female Humans Male Neoplasm Invasiveness Postoperative Complications/epidemiology/etiology Robotic Surgical Procedures/*methods Treatment Outcome Urinary Bladder Neoplasms/pathology/*surgery Urinary Diversion/adverse effects/*methods Ecud Extracorporeal urinary diversion Icud Intracorporeal urinary diversion Rarc

非肌层浸润性膀胱癌 经尿道激光 传统电切手术 Meta分析

*Carcinoma Transitional Cell Cystectomy/adverse effects Humans Morbidity Smoking/adverse effects *Urinary Bladder Neoplasms/epidemiology/surgery Complication Infection Outcome Perioperative mortality Radical cystectomy Smoking exposure Urothelial bladder cancer

Chemotherapy Adjuvant Cisplatin/therapeutic use Female Humans Male Muscles Randomized Controlled Trials as Topic *Urinary Bladder Neoplasms/drug therapy *Bladder cancer *Chemotherapy *Individual participant data *Meta-analysis *Systematic review

Humans Palliative Care Prospective Studies Quality of Life Retrospective Studies *Urinary Bladder Neoplasms/radiotherapy Radiotherapy bladder cancer bleeding palliation

Crohn's disease bladder cancer inflammatory bowel diseases meta-analysis ulcerative colitis commercial or financial relationships that could be construed as a potential conflict of interest.

Biomarkers Tumor/*urine Humans Ribonuclease Pancreatic/*urine Sensitivity and Specificity Urinary Bladder Neoplasms/*diagnosis/urine

Chemotherapy Adjuvant Humans Liquid Biopsy Muscles Neoplasm Invasiveness Prospective Studies *Urinary Bladder Neoplasms/drug therapy Cell-free DNA Circulating tumor cells Liquid biopsies Muscle-invasive bladder cancer Perioperative therapy

Administration Intravesical *Aneurysm Infected/therapy Aorta Humans *Mycobacterium bovis *Urinary Bladder Neoplasms/drug therapy

Administration Intravesical BCG Vaccine/*adverse effects/*therapeutic use Humans Meta-Analysis as Topic Randomized Controlled Trials as Topic *Systematic Reviews as Topic Urinary Bladder Neoplasms/*drug therapy

Disease-Free Survival *Dose Fractionation Radiation Humans Neoplasm Recurrence Local/epidemiology/pathology/*radiotherapy Radiation Dose Hypofractionation/*standards Risk Factors Treatment Outcome Urinary Bladder Neoplasms/epidemiology/pathology/*radiotherapy