首页膀胱肿瘤治疗及预后证据详情

[ICG lymphography and fluorescence in pelvic lymphadenectomy for bladder and prostate cancer.]

原文: 2019 年 发布于 World Journal of Urology 29 卷 第 01 期 E1044-E1044 浏览量:222次
文献简介

Background: Exposure to high levels of arsenic in drinking water has been associated with an increased risk of lung and bladder cancer, but the presence of an increased risk at low levels is questionable. Methods: A systematic review and a dose-response meta-analysis were conducted on risk estimates of lung and bladder cancer for exposure to arsenic in drinking water up to 150 mu g/L, using a 2-stage approach based on a random-effects model. Results: Five studies of lung cancer were identified; the meta-relative risk (RR) for an increase of 10 mu g/L arsenic level was 1.03 (95% confidence interval [CI]: 0.99-1.06; P heterogeneity = .05). The meta-analysis of bladder cancer included 8 studies; the meta-RR for an increase of 10 mu g/L arsenic level was 1.02 (95% CI: 0.97-1.07, P heterogeneity = .01). Sensitivity analyses, including a 1-stage meta-regression, confirmed the main findings. Conclusion: This systematic review and meta-analysis provided evidence of a lack of an increased risk of lung and bladder cancer for exposure to arsenic in drinking water up to 150 mu g/L, the highest concentration studied.

热门文献