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Aged China Databases Factual *Diabetes Mellitus/epidemiology Humans *Lower Urinary Tract Symptoms/complications/epidemiology Male *Prostatic Hyperplasia/complications *Luts *benign prostatic hyperplasia *diabetes mellitus *lower urinary tract symptoms *meta-analysis commercial or financial relationships that could be construed as a potential conflict of interest.

Benign prostatic hyperplasia Embolization therapeutic Lower urinary tract symptoms Meta-analysis Systematic review

Humans Incidence Male Pain Postoperative/*epidemiology Pelvic Pain/*epidemiology Prostatic Hyperplasia Transurethral Resection of Prostate/*adverse effects Dysuria Pain Prostate Prostatic hyperplasia Transurethral resection of prostate Urological surgical procedures

Humans Male Network Meta-Analysis *Prostatic Hyperplasia/surgery Quality of Life Randomized Controlled Trials as Topic *Transurethral Resection of Prostate Treatment Outcome *benign prostatic hyperplasia *network meta-analysis *prostate volume *surgical treatment conflicts of interest with respect to the research authorship and/or publication of this article.

Benign prostatic enlargement Benign prostatic hyperplasia Lower urinary tract symptoms Minimally invasive surgical therapies Prostatic urethral lift Rezum Temporary implantable nitinol device UroLift Water vapor thermal therapy iTind

Lower urinary tract symptoms Phytotherapy Prostatic hyperplasia Serenoa

Humans *Lower Urinary Tract Symptoms/surgery Male Minimally Invasive Surgical Procedures Network Meta-Analysis *Prostatic Hyperplasia/surgery *Transurethral Resection of Prostate Treatment Outcome *Aquablation *Bph *Rezum *Urolift *benign prostatic hyperplasia *network meta-analysis *prostatic urethral lift *water vapor therapy

Benign prostatic obstruction Convective radiofrequency thermotherapy Lower urinary tract symptoms Minimally invasive surgical procedures Prostatic urethral lift

Comparative Effectiveness Research Cost-Benefit Analysis Humans Male Operative Time *Postoperative Complications/etiology/therapy *Prostatectomy Prostatic Hyperplasia Recovery of Function *Robotic Surgical Procedures *Patient outcome assessment *Postoperative complications *Prostatectomy *Prostatic hyperplasia *Robotic surgical procedures

Cystectomy/*adverse effects Humans Male Neoplasm Recurrence Local/*diagnosis Prostatic Hyperplasia/diagnosis Transurethral Resection of Prostate/*adverse effects Urinary Bladder/*diagnostic imaging Urinary Bladder Neoplasms/diagnosis *#BladderCancer *#blcsm *Turbt *Turp *benign prostatic hyperplasia *bladder cancer *endoscopic surgery *simultaneous surgery

Ambulatory Surgical Procedures Feasibility Studies Humans *Laser Therapy *Lasers Solid-State Male *Prostatic Hyperplasia/surgery *Transurethral Resection of Prostate Treatment Outcome *Green-light *HoLEP *Turp *benign prostatic hyperplasia *laser surgery *outpatient surgery

Humans Lower Urinary Tract Symptoms Male Network Meta-Analysis Phytotherapy Plant Extracts Prostate/*drug effects Prostatic Hyperplasia/*drug therapy Randomized Controlled Trials as Topic *Serenoa Treatment Outcome *Benign prostatic hyperplasia *Lower urinary tract symptoms *Medical therapy *Phytotherapy *Prostate *Saw palmetto

5-alpha Reductase Inhibitors/administration & dosage/*adverse effects Alopecia/drug therapy Depression/*chemically induced/epidemiology Finasteride/administration & dosage/*adverse effects Humans Male Prostatic Hyperplasia/drug therapy Sexual Dysfunction Physiological/chemically induced/epidemiology Suicidal Ideation

5-alpha Reductase Inhibitors Androgen Antagonists Humans Male Plant Extracts/*pharmacology *Prostatic Hyperplasia/drug therapy Randomized Controlled Trials as Topic *Serenoa/chemistry Tamsulosin

5-alpha Reductase Inhibitors Humans Male Oxidoreductases Prospective Studies *Prostatic Hyperplasia/drug therapy *Prostatic Neoplasms/drug therapy 5?-reductase inhibitors Bph Prostate cancer cancer specific mortality meta-analysis

Adrenergic alpha-Antagonists Adult Aged Bias Cholinergic Antagonists Drug Therapy Combination Humans Lower Urinary Tract Symptoms Male Middle Aged Prostatic Hyperplasia Quality of Life Randomized Controlled Trials as Topic

*Endoscopy Humans Male Prostatectomy Prostatic Hyperplasia BipolEP DiLEP Eep HoLEP Systematic review ThuLEP research collaboration travel grants honorarium.

Acetanilides Adrenergic beta-3 Receptor Agonists Aged Humans Lower Urinary Tract Symptoms Male Prostatic Hyperplasia/complications/*drug therapy Randomized Controlled Trials as Topic Thiazoles Treatment Outcome Urinary Bladder Overactive/complications/*drug therapy Urological Agents Lower urinary tract symptoms Mirabegron Overactive Prostatic hyperplasia Urinary bladder

alfuzosin alpha adrenoreceptor antagonists benign prostatic hyperplasia low urinary tract symptoms pharmacology seminaries for Recordati Astellas Glaxo Smith Kline. Cosimo de Nunzio: Consultancy for Pierrefabre Janssen Sanofi Glaxo Smith Kline. Other authors have no additional conflict of interest to declare.