Humans Biomarkers Tumor *Carcinoma in Situ/diagnosis *Carcinoma Transitional Cell/pathology Hyaluronan Receptors/metabolism Keratin-20/analysis/metabolism Ki-67 Antigen/metabolism Tumor Suppressor Protein p53/analysis/metabolism Urinary Bladder *Urinary Bladder Neoplasms/pathology Urothelium/chemistry/metabolism/pathology Bladder carcinoma Carcinoma in situ Carcinoma vesical Displasia Dysplasia Immunomarkes Inmunomarcadores

Biomarkers Tumor/*metabolism Estrogen Receptor alpha/*metabolism Estrogen Receptor beta/*metabolism GATA3 Transcription Factor/*metabolism Humans Prognosis Urinary Bladder Neoplasms/diagnosis/*metabolism Gata3 bladder cancer estrogen receptors immunohistochemistry tumour markers commercial or financial relationships that could be construed as a potential conflict of interest.

Carcinogenesis/genetics/*immunology/pathology *Genetic Predisposition to Disease Humans Inflammation/genetics/*immunology/pathology *Polymorphism Single Nucleotide Receptors Interleukin/*genetics Urinary Bladder Neoplasms/genetics/*immunology/pathology Bladder urothelial carcinoma Gene polymorphism Interleukin 17 Interleukin 23 Interleukin-23 receptor Natural killers Tumour-associated macrophages

Carcinoma Transitional Cell/*drug therapy Humans Prognosis Receptors Fibroblast Growth Factor/*antagonists & inhibitors Urinary Bladder Neoplasms/*drug therapy Bladder cancer Fgfr FGFR inhibitors Fgfr3 Progression Urothelial carcinoma

25-Hydroxyvitamin D3 1-alpha-Hydroxylase/metabolism Cell Line Tumor Humans Receptors Calcitriol/metabolism Risk Factors Signal Transduction Urinary Bladder Neoplasms/*blood/etiology/metabolism Vitamin D/*analogs & derivatives/blood/metabolism Vitamin D Deficiency/*blood/complications/metabolism 1 25(oh)(2)d 1α-hydroxylase Bladder cancer Cathelicidin Vitamin D

Estrogen Receptor alpha/metabolism Estrogen Receptor beta/metabolism Female Humans Immunohistochemistry/*methods Male Prognosis Receptors Androgen/metabolism Retrospective Studies Software Urinary Bladder Neoplasms/*metabolism/pathology