Arteries *Embolization Therapeutic Humans *Lower Urinary Tract Symptoms/etiology Male *Prostatic Hyperplasia/complications/therapy *Radiation Exposure Treatment Outcome *Benign prostatic hyperplasia *Lower urinary tract symptoms *Minimally invasive treatment *Prostatic artery embolisation

Benign prostatic hyperplasia Embolization therapeutic Lower urinary tract symptoms Meta-analysis Systematic review

*Embolization Therapeutic Humans *Lower Urinary Tract Symptoms/etiology/therapy Male *Prostatic Hyperplasia/complications/therapy Quality of Life Treatment Outcome

Aged Arteries Embolization Therapeutic Humans Male Prostate/*blood supply/surgery Prostatic Hyperplasia/surgery/*therapy Reference Standards Transurethral Resection of Prostate Treatment Outcome

Benign prostatic hyperplasia lower urinary tract symptoms doxazosin gastro-intestinal therapeutic system tamsulosin

Aged Arteries Ejaculation Embolization Therapeutic Humans Lower Urinary Tract Symptoms/*therapy Male Penile Erection Postoperative Complications/etiology Prostate/*blood supply Prostatic Hyperplasia Quality of Life Randomized Controlled Trials as Topic Retreatment/statistics & numerical data Sexual Dysfunction Physiological/etiology *Transurethral Resection of Prostate Treatment Outcome

Acrylic Resins/administration & dosage Embolization Therapeutic Gelatin/administration & dosage Humans Male Particle Size Polyvinyl Alcohol/administration & dosage Prostate/*blood supply Prostatic Hyperplasia/*therapy Radiography Interventional

Adult Embolization Therapeutic/*adverse effects/methods Humans Lower Urinary Tract Symptoms/*etiology Male Middle Aged Patient Reported Outcome Measures Penile Erection/physiology Prostate/blood supply Prostatic Hyperplasia/*therapy Randomized Controlled Trials as Topic Safety Treatment Outcome Benign prostatic hyperplasia Lower urinary tract symptoms Prostatic artery embolization Systematic review

Embolization Therapeutic Humans Male Prostate/*blood supply/pathology Prostatic Hyperplasia/diagnosis/*therapy Transurethral Resection of Prostate Treatment Outcome Benign prostatic hyperplasia Meta-analysis Prostatic artery embolization Transurethral resection of the prostate PUBLICATION: Not applicable. COMPETING INTERESTS: The authors declare that they have no competing interests. PUBLISHER’S NOTE: Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Arteries Embolization Therapeutic/*adverse effects/methods/standards Humans Kallikreins/blood Lower Urinary Tract Symptoms/blood/etiology/*therapy Male Practice Guidelines as Topic Prostate/blood supply Prostate-Specific Antigen/blood Prostatic Hyperplasia/blood/complications/*therapy Quality of Life Treatment Outcome *arteries *embolization *investigational *prostatic hyperplasia *therapeutic *therapies *treatment outcome

Aged Causality Comorbidity Embolization Therapeutic/*statistics & numerical data Follow-Up Studies Humans Longitudinal Studies Lower Urinary Tract Symptoms/*epidemiology/*prevention & control Male Middle Aged Prostate/blood supply Prostatic Hyperplasia/diagnostic imaging/*epidemiology/*therapy Risk Factors Treatment Outcome

Aged Embolization Therapeutic Humans Lower Urinary Tract Symptoms/complications/therapy Male Prostate/blood supply/diagnostic imaging Prostatic Hyperplasia/complications/*therapy Treatment Outcome Bph Prostate artery embolisation Quality of life

Adrenergic alpha-Antagonists/administration & dosage/*therapeutic use Cholinergic Antagonists/administration & dosage Drug Therapy Combination Humans *Lower Urinary Tract Symptoms Male Prostatic Hyperplasia/*diagnosis/*drug therapy Publication Bias Quality of Life Treatment Outcome

*Arteries Embolization Therapeutic Humans Lower Urinary Tract Symptoms/etiology Male Prostate/*blood supply Prostatic Hyperplasia/complications/diagnosis/*therapy Quality of Life Risk Factors Time Factors Treatment Outcome

Embolization Therapeutic Humans Lower Urinary Tract Symptoms/*therapy Male Prostate/*blood supply Prostatic Hyperplasia/physiopathology/*therapy benign prostatic hyperplasia lower urinary tract symptoms meta-analysis prostate artery embolization

*Arteries/diagnostic imaging Embolization Therapeutic Humans Kallikreins/blood Male Prostate/*blood supply Prostate-Specific Antigen/blood Prostatic Hyperplasia/diagnostic imaging/*therapy Quality of Life Time Factors Treatment Outcome

Humans Immune Checkpoint Inhibitors/therapeutic use *Carcinoma Transitional Cell/drug therapy *Urinary Bladder Neoplasms/drug therapy Proportional Hazards Models Eastern Cooperative Oncology Group Immune checkpoint inhibitor Performance status Urothelial carcinoma

Humans *Gemcitabine Docetaxel/therapeutic use BCG Vaccine/adverse effects Adjuvants Immunologic *Urinary Bladder Neoplasms/therapy Administration Intravesical Neoplasm Invasiveness Neoplasm Recurrence Local

Humans *Adjuvants Immunologic/therapeutic use/adverse effects Administration Intravesical Neoplasm Recurrence Local/epidemiology *Urinary Bladder Neoplasms/pathology Drug Administration Schedule Bcg Cvnmi Desabastecimiento Dosis completa Dosis reducida Full dose Nmibc Reduced dose Shortage

Humans *Urinary Bladder Neoplasms/surgery/pathology Urologic Surgical Procedures Cystectomy *Laser Therapy *Lasers Solid-State/therapeutic use Turbt bladder tumor laser resection recurrence