膀胱癌根治性切除术后肠梗阻的危险因素 Meta 分析
原文： 2022 年 发布于
微创泌尿外科杂志
17 卷 第 6 期 944451
浏览量：164次
作者：
张世豪
作者单位：
Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria
Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan. Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria
Department of Urology, The Jikei University School of Medicine, Tokyo, Japan. Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria
Institute for Urology and Reproductive Health, Sechenov University, Moscow, Russia. Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria
Department of Urology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria
Department of Urology, Jagiellonian University Medical College, Cracow, Poland. Department of Urology UROSUD, La Croix Du Sud Hospital, Quint Fonsegrives, France. Department of Surgery, S.H. Ho Urology Centre, The Chinese University of Hong Kong, Hong Kong, China. Department of Urology, Second Faculty of Medicine of Charles University, University Hospital Motol, Prague, Czech Republic. Department of Urology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan. Department of Urology, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria
Institute for Urology and Reproductive Health, Sechenov University, Moscow, Russia
Division of Urology, Department of Special Surgery, The University of Jordan, Amman, Jordan
Department of Urology, University of Texas Southwestern Medical Center, Dallas, TX
Department of Urology, Second Faculty of Medicine, Charles University, Prague, Czech Republic
Department of Urology, Weill Cornell Medical College, New York, NY, USA
Karl Landsteiner Institute of Urology and Andrology, Vienna, Austria. Electronic address: shahrokh.shariat@meduniwien.ac.at.
归属分类：
膀胱肿瘤病因/危险因素证据
DOI：
10.1007/s40273-023-01256-9
关键词：
新辅助化疗
肌层浸润性膀胱癌
疗效
安全性
Meta分析
目的 : 通过 Meta 分析探讨膀胱癌根治性切除术后肠梗阻的危险因素。方法 : 计算机检索维普数据库 (VIP) 、万方数据库 (Wanfang data) 、中国生物医学文献数据库 (CBM) 、中国知网 (CNKI) 、 Pub Med 、 The Cochrane Library, 收集有关膀胱癌患者根治术后肠梗阻危险因素的病例对照研究、队列研究和横断面研究。检索时限从建库至 2022 年 1 月。由研究者独立进行文献筛选、资料提取和质量评价 , 采用 Rev Man 5.4 软件进行 Meta 分析。结果 : 在本 Meta 分析中 , 共纳入 9 篇文献 , 探讨了 13 个危险因素 , 通过 Revman5.4 软件进行 Meta 分析 , 得出危险因素 SMD/OR 及 95%CI: 年龄 [SMD=0.40,95%CI(0.20,0.61)] 、 BMI[SMD=0.48,95%CI(0.29,0.68)] 、回肠膀胱尿流改道 [SMD=2.45,95%CI(1.51,3.97)] 、术前白蛋白 [SMD=-0.10,95%CI(-0.31,0.12)] 、术前血肌酐 [SMD=-0.01,95%CI(-0.38,0.37)] 、术前血红蛋白 [SMD=-0.08,95%CI(-0.27,0.12)] 、手术时间 [SMD=0.11,95%CI(-0.11,0.32)] 、术中是否输血 [OR=0.68,95%CI(0.42,1.07)] 、术中出血量 [SMD=0.07,95%CI(-0.15,0.28)] 、 ASA 评分 >2 分 [OR=1.39,95%CI(0.31,6.23)] 、肿瘤病理分期 [OR=1.01,95%CI(0.73,1.40)] 。年龄、 BMI 、回肠膀胱尿流改道 P<0.05, 是膀胱癌根治性切除术后肠梗阻的危险因素。结论 : 现有证据表明 , 年龄、 BMI 、回肠膀胱尿流改道是膀胱癌根治性切除术后肠梗阻的危险因素。受纳入文献数量和质量限制 , 本研究结论仍需要更多高质量的研究予以证实。