Aging Androgens/metabolism Anti-Inflammatory Agents Humans Inflammation Male *Prostatic Hyperplasia benign prostatic hyperplasia disease progression pathogenesis commercial or financial relationships that could be construed as a potential conflict of interest.

Benign prostate hyperplasia Genetic polymorphism Lower urinary tract symptoms Meta-analysis Systematic review

*Alleles Ethnicity/genetics *Genetic Association Studies *Genetic Predisposition to Disease Genotype Humans Male Odds Ratio *Polymorphism Single Nucleotide Prostate-Specific Antigen/*genetics Prostatic Hyperplasia/*genetics Publication Bias Risk Factors Bph Psa meta-analysis polymorphism

Male Humans *Stomach Neoplasms/genetics *Urinary Bladder Neoplasms/genetics Urinary Bladder Membrane Proteins RNA Messenger Antigens Neoplasm/genetics Neoplasm Proteins GPI-Linked Proteins/genetics Psca cancer risk polymorphism rs2294008 (C/T)

Humans *Carcinoma Transitional Cell/pathology *Urinary Bladder Neoplasms/genetics DNA Methylation Neoplasm Recurrence Local/genetics Prognosis *Urologic Neoplasms/genetics/pathology Membrane Proteins/genetics Neoplasm Proteins/genetics Biomarkers Kaplan-Meier survival Meta-analysis Methylation Upper tract urothelial carcinoma

Male Humans *Papillomavirus Infections/complications/epidemiology/prevention & control Human Papillomavirus Viruses Mendelian Randomization Analysis Papillomaviridae/genetics Human papillomavirus 18 *Urinary Bladder Neoplasms/epidemiology/complications HPV prevalence bladder cancer human papillomavirus mendelian randomization meta-analysis

Humans Female *Carcinoma Transitional Cell/chemically induced/epidemiology/genetics DNA Adducts/adverse effects *Drugs Chinese Herbal/adverse effects Taiwan/epidemiology *Urinary Bladder Neoplasms Carcinogens *Kidney Neoplasms/chemically induced/epidemiology/genetics *Aristolochic Acids/adverse effects/analysis *Ureteral Neoplasms/chemically induced/epidemiology *Urinary Tract Aristolochia DNA adduct Mass spectrometry Nephropathy Renal pelvic cancer Ureteral cancer

bladder cancer germline monogenic gene pathogenic mutations risk

*Cell Cycle Proteins/genetics Humans Prospective Studies Sensitivity and Specificity *Urinary Bladder Neoplasms/diagnosis/pathology Adxbladder Biomarker Bladder cancer Diagnostic accuracy Mcm5 Systematic review

Biomarkers/urine Carcinogenesis Carcinogens/toxicity Female Humans Male *Tobacco Products/adverse effects *Urinary Bladder Neoplasms/etiology Biomarkers of exposure Bladder cancer Carcinogens Heated tobacco product Urine disclosures.

Asian People/genetics Genetic Predisposition to Disease Humans *Methylenetetrahydrofolate Reductase (NADPH2)/genetics Polymorphism Single Nucleotide *Urinary Bladder Neoplasms/genetics Folate Mthfr Polymorphism Urinary Neoplasms bladder cancer

Bcg Bacillus Calmette–Guérin Nmibc bladder cancer checkpoint inhibition therapy nadofaragene firadenovec non muscle invasive oncolytic viruses

Female Gene Expression Profiling Gene Regulatory Networks Humans Male Muscles Neoplasm Invasiveness Prognosis *Urinary Bladder Neoplasms/genetics/metabolism rab GTP-Binding Proteins/genetics/metabolism Bladder cancer Gene expression Muscle-invasive bladder cancer Urothelial cancer

Humans Female Male *Urinary Bladder Neoplasms/etiology/microbiology RNA Ribosomal 16S/genetics Urinary Bladder/microbiology *Microbiota/genetics Bacteria/genetics Bladder cancer Gender Urinary microbiota Uropathogens of interest.

Apoptosis B7-H1 Antigen/genetics/metabolism *Carcinoma Transitional Cell/pathology Cystectomy Humans Immune Checkpoint Inhibitors Ligands Lymph Node Excision Neoplasm Recurrence Local/pathology Prognosis Programmed Cell Death 1 Receptor Urinary Bladder *Urinary Bladder Neoplasms/pathology bladder urothelial carcinoma meta-analysis prognostic value programmed cell death ligand-1 radical cystectomy commercial or financial relationships that could be construed as a potential conflict of interest.

Autoantigens Biomarkers Tumor/genetics/metabolism Gene Expression Regulation Neoplastic Humans Procollagen-Lysine 2-Oxoglutarate 5-Dioxygenase/genetics/metabolism Prognosis *Urinary Bladder Neoplasms/pathology Bladder cancer Meta-analysis Microarray datasets Overall survival Prognostic biomarker

Case-Control Studies Humans Male NAD(P)H Dehydrogenase (Quinone)/*genetics Polymorphism Single Nucleotide Prostatic Neoplasms/*genetics Urinary Bladder Neoplasms/*genetics NQO1 gene meta-analysis polymorphism prostatic neoplasms urinary bladder neoplasms

Carcinogenesis/genetics/*immunology/pathology *Genetic Predisposition to Disease Humans Inflammation/genetics/*immunology/pathology *Polymorphism Single Nucleotide Receptors Interleukin/*genetics Urinary Bladder Neoplasms/genetics/*immunology/pathology Bladder urothelial carcinoma Gene polymorphism Interleukin 17 Interleukin 23 Interleukin-23 receptor Natural killers Tumour-associated macrophages

Carcinoma Transitional Cell/*classification/*genetics/mortality Humans Predictive Value of Tests Survival Rate Treatment Outcome Urinary Bladder Neoplasms/*classification/*genetics/mortality Bladder cancer Molecular classification Molecular subtype Prognosis Progression Urothelial carcinoma

Asia Asian People Humans *MicroRNAs/genetics *Urinary Bladder Neoplasms/diagnosis/genetics