Cystectomy/methods Humans Learning Curve Postoperative Complications/etiology/surgery *Robotic Surgical Procedures/methods *Robotics Treatment Outcome *Urinary Bladder Neoplasms/surgery bladder cancer cystectomy systematic review

Blood Loss Surgical/statistics & numerical data Blood Transfusion/statistics & numerical data Cystectomy/*methods Female Humans Male Neoplasm Invasiveness Postoperative Complications/epidemiology/etiology Robotic Surgical Procedures/*methods Treatment Outcome Urinary Bladder Neoplasms/pathology/*surgery Urinary Diversion/adverse effects/*methods Ecud Extracorporeal urinary diversion Icud Intracorporeal urinary diversion Rarc

Cystectomy/adverse effects/*methods Humans Treatment Outcome Urethra Urinary Bladder Neoplasms/*surgery Bipolar Monopolar Systematic review Turbt

bladder cancer incidence meta-analyses metformin treatment outcome commercial or financial relationships that could be construed as a potential conflict of interest.

Cystectomy/*methods Electrosurgery/*methods Humans Neoplasm Invasiveness Treatment Outcome Urethra Urinary Bladder Neoplasms/pathology/*surgery Bipolar Meta-analysis Monopolar Transurethral bladder tumor resection

Humans *Laser Therapy/adverse effects Neoplasm Invasiveness Treatment Outcome Urinary Bladder Neoplasms/pathology/*surgery

Disease-Free Survival *Dose Fractionation Radiation Humans Neoplasm Recurrence Local/epidemiology/pathology/*radiotherapy Radiation Dose Hypofractionation/*standards Risk Factors Treatment Outcome Urinary Bladder Neoplasms/epidemiology/pathology/*radiotherapy

*Clinical Protocols *Cystectomy/methods *Enhanced Recovery After Surgery Humans Time Factors Treatment Outcome Urinary Bladder Neoplasms/*surgery Cystectomy Eras Fast track Meta-analysis Protocol Systematic review evidence-based medicine

Carcinoma Transitional Cell/*classification/*genetics/mortality Humans Predictive Value of Tests Survival Rate Treatment Outcome Urinary Bladder Neoplasms/*classification/*genetics/mortality Bladder cancer Molecular classification Molecular subtype Prognosis Progression Urothelial carcinoma

Carcinoma in Situ/*diagnosis/*therapy Humans Treatment Outcome Urinary Bladder Neoplasms/*diagnosis/*therapy Bladder cancer Carcinoma in situ Non–muscle-invasive bladder cancer

Adjuvants Immunologic/*administration & dosage Administration Intravesical BCG Vaccine/*administration & dosage Humans *Lymphocytes Tumor-Infiltrating Treatment Outcome Urinary Bladder Neoplasms/*drug therapy/immunology/*pathology

Adjuvants Immunologic/therapeutic use BCG Vaccine/therapeutic use Evidence-Based Medicine Humans Neoplasm Invasiveness Neoplasm Recurrence Local/*therapy Treatment Outcome Urinary Bladder Neoplasms/pathology/*therapy Bacillus Calmette-Guerin unresponsive Bladder preservation therapy Bladder sparing Non–muscle-invasive bladder cancer

Aged Cystectomy/adverse effects/*methods/statistics & numerical data Humans Male Middle Aged Postoperative Complications Quality of Life Randomized Controlled Trials as Topic Robotic Surgical Procedures/adverse effects/*methods/statistics & numerical data Treatment Outcome Urinary Bladder Neoplasms/*surgery

Administration Intravesical Antibiotics Antineoplastic/administration & dosage/*therapeutic use BCG Vaccine Carcinoma Transitional Cell/*drug therapy Humans Mitomycin/administration & dosage/*therapeutic use Randomized Controlled Trials as Topic Treatment Outcome Urinary Bladder Neoplasms/*drug therapy

Antineoplastic Combined Chemotherapy Protocols/*therapeutic use Carcinoma Transitional Cell/immunology/mortality/pathology/*therapy Chemotherapy Adjuvant/methods/statistics & numerical data Clinical Trials Phase I as Topic Clinical Trials Phase II as Topic Cystectomy Disease-Free Survival Follow-Up Studies Humans Immune Checkpoint Inhibitors/*therapeutic use Muscle Smooth/pathology/surgery Neoadjuvant Therapy/*methods/statistics & numerical data Neoplasm Invasiveness/pathology Prospective Studies Treatment Outcome Urinary Bladder/pathology/surgery Urinary Bladder Neoplasms/immunology/mortality/pathology/*therapy Bladder cancer Immune checkpoint inhibitors Immunotherapy Neoadjuvant

Cystectomy/adverse effects Humans Postoperative Complications/diagnosis/epidemiology/etiology Risk Factors *Robotic Surgical Procedures/adverse effects *Robotics Treatment Outcome *Urinary Bladder Neoplasms/surgery Urologic Surgical Procedures *Urology Complications European Association of Urology guidelines Outcome reporting Robot-assisted radical cystectomy Standardised tool

Aged Catheterization Female Hospitalization Humans Lasers Solid-State/*therapeutic use Male Middle Aged Muscles/*pathology Neoplasm Recurrence Local/pathology Postoperative Complications/etiology Publication Bias Treatment Outcome Urethral Stricture/surgery Urinary Bladder Neoplasms/pathology/*surgery *Urologic Surgical Procedures Holmium laser Meta-analysis Non-muscle-invasive bladder cancer Transurethral resection

Adult Aged Aged 80 and over B7-H1 Antigen/genetics/*immunology Female Humans Immune Checkpoint Inhibitors/*administration & dosage *Immunotherapy Male Middle Aged Programmed Cell Death 1 Receptor/genetics/*immunology Progression-Free Survival Randomized Controlled Trials as Topic Treatment Outcome Urinary Bladder Neoplasms/genetics/immunology/mortality/*therapy efficacy immunotherapy meta-analysis safety urothelial cancer this study.

Cystectomy/adverse effects/*methods Humans Laser Therapy/adverse effects/*methods Neoplasm Invasiveness Treatment Outcome Urethra Urinary Bladder Neoplasms/pathology/*surgery Bladder cancer Laser surgery Systematic review and meta-analysis Transurethral resection

Chemotherapy Adjuvant *Cystectomy/methods Humans Neoadjuvant Therapy Smoking/*adverse effects Survival Rate Treatment Outcome Urinary Bladder Neoplasms/drug therapy/*mortality/*surgery cigarette smoking cystectomy recurrence survival urinary bladder neoplasms