Humans Muscle Skeletal/*pathology Neoplasm Invasiveness ROC Curve Radiography/*methods Research Design Urinary Bladder Neoplasms/*diagnosis Bladder cancer Diagnostic imaging Magnetic resonance imaging

Antineoplastic Combined Chemotherapy Protocols/*therapeutic use Chemotherapy Adjuvant *Cystectomy/methods Humans Neoadjuvant Therapy Neoplasm Invasiveness Survival Rate Urinary Bladder Neoplasms/*drug therapy/mortality/pathology/*surgery Muscle-invasive bladder cancer Neoadjuvant chemotherapy Overall survival Radical cystectomy

Androgen Antagonists/*therapeutic use Humans Male Observational Studies as Topic Prostatic Neoplasms/*drug therapy Risk Assessment Urinary Bladder Neoplasms/epidemiology/*prevention & control Androgen deprivation therapy Bladder cancer Pharmacoepidemiology Prostate cancer Systematic review

Arylamine N-Acetyltransferase/*genetics Asian People/genetics Humans *Polymorphism Single Nucleotide Smoking/epidemiology Urinary Bladder Neoplasms/epidemiology/ethnology/*genetics White People/genetics Bladder cancer Meta-analysis N-acetyltransferase 2 Polymorphism competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Biomarkers Carcinogens/analysis *Electronic Nicotine Delivery Systems Humans *Urinary Bladder Neoplasms/diagnosis/epidemiology/etiology *Vaping Bladder cancer Carcinogens Electronic cigarette Urinary biomarkers

Biomarkers Tumor/*metabolism Humans RNA Long Noncoding/*metabolism Urinary Bladder Neoplasms/*diagnosis/*genetics/pathology bladder cancer lncRNAs meta-analysis non-invasive diagnosis

*Cystectomy/methods Humans Postoperative Complications/*epidemiology Prognosis Survival Rate Urinary Bladder Neoplasms/*mortality/*surgery Bladder cancer clinical markers morbidity mortality radical cystectomy survival

Adult Aged Aged 80 and over Female *Health Services Needs and Demand Humans Male Middle Aged Sexual Dysfunction Physiological/*etiology *Sexual Health Urinary Bladder Neoplasms/*complications/*therapy Bladder cancer Health-related quality of life Mental wellbeing Radical cystectomy Sexual health

Biomarkers/urine DNA Mutational Analysis DNA Neoplasm/*urine Disease Progression Humans Mutation Neoplasm Recurrence Local/*diagnosis/genetics/*urine Sensitivity and Specificity Urinary Bladder Neoplasms/*diagnosis/genetics/*urine #BladderCancer #blcsm biomarkers molecular diagnostics urinary bladder neoplasms urine analysis Amsterdam UMC location VUmc. J. Bosschieter R.D.M. Steenbergen and J.A. Nieuwenhuijzen are inventors on patent(s) related to the work.

*Anesthesia Spinal Cystectomy Humans Obturator Nerve Ultrasonography Interventional *Urinary Bladder Neoplasms/surgery

*Cystectomy/methods *Enhanced Recovery After Surgery Humans Length of Stay Treatment Outcome Urinary Bladder Neoplasms/*surgery Cystectomy Enhanced Recovery After Surgery Enhanced recovery Outcomes

Aged Carcinoma Transitional Cell/*surgery *Cystectomy/methods Female Humans *Lymph Node Excision Male Middle Aged Postoperative Complications Randomized Controlled Trials as Topic Treatment Outcome Urinary Bladder Neoplasms/*surgery

Anesthetics Local/*therapeutic use *Cystoscopy Humans Lidocaine/*therapeutic use Male Pain Management/*methods Pain Measurement Randomized Controlled Trials as Topic Urinary Bladder Neoplasms/diagnosis/therapy administration cystoscopy intravesical lidocaine pain procedural urinary bladder neoplasms

Carcinoma Transitional Cell/diagnosis/epidemiology/*therapy Child Combined Modality Therapy *Disease Management Disease Progression Global Health Humans Incidence Risk Factors Survival Rate/trends Urinary Bladder/*pathology Urinary Bladder Neoplasms/diagnosis/epidemiology/*therapy Management Pediatric Surveillance Transurethral resection Urothelial cell carcinoma

Coloring Agents Humans Indocyanine Green Lymph Node Excision *Lymphatic Metastasis/diagnostic imaging *Lymphography Male Pelvis *Prostatic Neoplasms/diagnostic imaging/pathology Sentinel Lymph Node Biopsy *Urinary Bladder Neoplasms/diagnostic imaging/pathology Cáncer de Próstata Ganglio centinela Linfadenectomía Lymph node dissection Prostate cáncer Sentinel lymph node Verde de Indocianina

Humans Patient Outcome Assessment *Patient Reported Outcome Measures Quality of Life Randomized Controlled Trials as Topic Reproducibility of Results Urinary Bladder Neoplasms/*diagnosis/pathology/psychology/*therapy Early bladder cancer Non-muscle invasive bladder cancer Patient-reported outcome measures Systematic review

Anastomosis Surgical/adverse effects/instrumentation/methods Constriction Pathologic/etiology Cystectomy/*instrumentation/methods Humans Ileum/surgery Incidence Postoperative Complications/etiology Stents/*adverse effects Ureter/surgery Ureteral Obstruction/*etiology Urinary Bladder Neoplasms/surgery Urinary Catheters/adverse effects Urinary Diversion/adverse effects/*instrumentation/methods Cystectomy Internal double-J stent Orthotopic neobladder Ureteroileal anastomosis stricture Urinary diversion

Anxiety/therapy Cystectomy/*psychology Depression/therapy *Exercise Therapy Humans Physical Fitness Quality of Life Urinary Bladder Neoplasms/*psychology/*surgery Bladder cancer exercise psychosocial interventions radical cystectomy

Adult Aged Air Pollution/*adverse effects Carcinogens Environmental/*adverse effects Cohort Studies Environmental Exposure/*adverse effects Europe/epidemiology Female Humans Incidence Male Meta-Analysis as Topic Middle Aged Nitrogen Oxides/adverse effects Particulate Matter/adverse effects Prospective Studies Risk Factors Urinary Bladder Neoplasms/*epidemiology/etiology Air pollution Bladder cancer Environment Prevention

Humans Odds Ratio Prospective Studies *Urinary Bladder Neoplasms *Vitamin E bladder cancer meta-analysis vitamin E